[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Scientific Journal of Kurdistan University of Medical Sciences ::
Back to the articles list Back to browse issues page
Investigating of dietary nitrate and nitrite interaction and vitamin C and urinary and serum nitrate and nitrite levels: Tehran Lipid and Glucose Study
Zahra Saeedirad1 , Zahra Bahadoran1 , Maryam Mousavi1 , Parvin Mirmiran 2, Fereidoun Azizi1
1- Shahid Beheshti University of Medical Sciences
2- Shahid Beheshti University of Medical Sciences , mirmiran@endocrine.ac.ir
Abstract:   (58 Views)
Background and purpose: studies show that antioxidants prevent conversion of NO3/NO2 to nitrosamines compounds. tha aim of this study was to determine the potential effect of interaction between dietary intakes of vitamin C and NO3/NO2 on urinary and serum levels of NO3/NO2.
Materials and Methods: This cross-sectional study included 251 adults aged >19 years was performed in the phase 6 of  the Tehran Lipid and Glucose Study in 2015. Food intake was assessed using a semi-quantitative food frequency questionnaire. The average daily intake of nitrate and nitrite and vitamin C was estimated. Serum and urine levels of nitrate and nitrite were measured using  the Grease method. In order to determine the effect of vitamin C on the interaction of nitrate and nitrite in urine and serum, linear regression test was used to modify the effects of confounders.
Results: There was a significant correlation between intake of nitrate and its urine level, above the median level of vitamin C intake (B = 0/004, P-value = 0/004). Also, this correlation remained significant after adjusting for age, sex, body mass index, calorie intake (B = 0.03, P-value = 0/001). The effect of vitamin C interactions on nitrate intake and urine level in the adjusted model for nitrate and nitrite was also found to be significant (B = 0/003 P-value = 0/001).
Conclusion: Increased intake of vitamin C significantly increases urinary excretion of nitrate and it is effective in  the interaction between dietary intakes and urinary excretion of nitrate.
Keywords: nitrate, nitrite, vitamin C
     
Type of Study: Applicable | Subject: General
Received: 2018/12/4 | Accepted: 2020/12/20
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print



Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Back to the articles list Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4331