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Comparison of the effect before and after intracorpus cavernosum Platelet-rich plasma injection in imporoving sexual function in men with erectile dysfunction
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Peyman Hayati1    , Rezgar Daneshdoost , Pouya Fattahi , Khaled Rahmani |
| 1- , peymanhayati1995@gmail.com |
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Abstract: (37 Views) |
Background and Aim: Erectile dysfunction (ED) is a common problem among men, and the use of platelet-rich plasma (PRP) therapy for the treatment of ED has attracted increasing attention, but there is still no definitive evidence of its effectiveness. The aim of this study was to compare the effect before and after intracorpus cavernosum PRP injection in improving sexual function in men with erectile dysfunction.
Materials and methods: This is a single-arm, before-and-after interventional study without any randomization was conducted on 32 men with erectile dysfunction who referred to Kowsar Hospital in Sanandaj. In this study, after completing demographic characteristics, their sexual dysfunction score was measured using the IIEF questionnaire. Then, the PRP subjects filled out the questionnaire on days 0, 20, 40, and 60 after receiving each. Evaluation of outcome indicators 20 days later, 40 days later, and 60 days after receiving PRP was performed. The most important outcome indicator is the sexual function of the patients, which was measured using the following questionnaire (IIEF). For data analysis, considering the qualitative nature of the dependent variable, t-test, chi-square, and logistic regression tests were used. For all tests, a significance level of 0.05 was considered.
Results: The results of the study showed that the average age of the patients was 57.31 years. The results showed that the average total score before injection was 7.43± 2.63, twenty days after injection was 9.87±3.53, forty days after injection was 10.81±3.52, and the average total score sixty days after injection was 11.46±3.81. The analytical results showed that there was a significant difference between the score of sufficient erection before and after injection (20, 40, 60 days), sufficient erection for penetration, sufficient erection after penetration before injection and twenty days after injection. There was also a significant difference between the average total score before injection and after injection (days 20, 40, and 60), and it seems that intracorpus cavernosum PRP injection had a significant effect on restoring normal erectile function and satisfaction with sexual function of the subjects studied. (P<0.0001). However, no statistically significant difference was observed between the score of maintaining erection until completion of intercourse before and after injection (P>0.05).
Conclusion: PRP treatment for erectile dysfunction has shown promising efficacy and has the potential to become a new alternative treatment option for patients with erectile dysfunction. |
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| Keywords: Intracorpus cavernosum injection, PRP, sexual function, erectile dysfunction |
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Type of Study: Original Research |
Subject:
Medicine - Urology
Received: 2026/06/8 | Accepted: 2026/08/10
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