1. Piero M, Nzaro G, Njagi J. Diabetes mellitus-a devastating metabolic disorder. Asian J Biomed Pharm 2015; 40: 1-7. [ DOI:10.15272/ajbps.v4i40.645] 2. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2010; 33: 62–9. [ DOI:10.2337/dc10-S062] 3. Gao HX, Regier EE, Close KL. International Diabetes Federation World Diabetes Congress 2015. J Diabetes 2016; 8: 300–2. [ DOI:10.1111/1753-0407.12377] 4. L'Heveder R, Nolan T. International diabetes federation. Diabetes Res Clin Pract 2013; 101: 349-51. [ DOI:10.1016/j.diabres.2013.08.003] 5. Palmeira CM, Santos DL, Seiça R, Moreno AJ, Santos MS. Enhanced mitochondrial testicular antioxidant capacity in Goto-Kakizaki diabetic rats: role of coenzyme Q. Am J Physiol Cell Physiol 2001; 281: C1023-C8. [ DOI:10.1152/ajpcell.2001.281.3.C1023] 6. Khaki A, Nouri M, Fathiazad F, Ahmadi-Ashtiani H, Rastgar H, Rezazadeh S. Protective effects of quercetin on spermatogenesis in streptozotocin-induced diabetic rat. J Med Plants 2009; 1: 57-64. 7. Ramalho-Santos J, Amaral S, Oliveira PJ. Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species. Curr Diabetes Rev 2008; 4: 46-54. [ DOI:10.2174/157339908783502398] 8. Jiang GY. Practical Diabetes. 1nd ed. Beijing: People's Health Publishing House, 1996: 295. 9. Murray FT, Cameron DF, Vogel RB, Thomas RG, Wyss hU, Zauner CW. The pituitary‐testicular axis at rest and during moderate exercise in males with diabetes mellitus and normal sexual function. J Androl 1988; 9: 197-206. [ DOI:10.1002/j.1939-4640.1988.tb01034.x] 10. Pitteloud N, Hardin M, Dwyer AA, Valassi E, Yialamas M, Elahi D, et al. Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab 2005; 90: 2636-41. [ DOI:10.1210/jc.2004-2190] 11. Cameron DF, Murray FT, Drylie DD. Interstitial compartment pathology and spermatogenic disruption in testes from impotent diabetic men. Anat Rec 1985; 213: 53-62. [ DOI:10.1002/ar.1092130108] 12. Vignon F, Le Faou A, Montagnon D, Pradignac A, Cranz C, Winiszewsky P, et al. Comparative study of semen in diabetic and healthy men. Diabete Metab 1991; 17: 350-4. 13. Ballester J, Munõz MC, Domínguez J, Rigau T, Guinovart JJ, Rodríguez‐Gil JE. Insulin‐dependent diabetes affects testicular function by FSH‐and LH‐linked mechanisms. J Androl 2004; 25: 706-19. [ DOI:10.1002/j.1939-4640.2004.tb02845.x] 14. Hagh Nazari S, Keifi N, editors. Saffron and various fraud matter in its production and trade. 2nd International Symposium on Saffron Biology and Technology. 2006 Oct. 28–30, Mashhad, Iran. 15. Hosseinzadeh H, Ziaee T, Sadeghi A. The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats. Phytomedicine 2008; 15: 491-5. [ DOI:10.1016/j.phymed.2007.09.020] 16. Singla RK, Bhat VG. Crocin: an overview. Glo J Pharmaceu Sci 2011; 1: 281-6. 17. Bathaie SZ, Bolhassan A, Tamanoi F. Anticancer effect and molecular targets of saffron carotenoids. Enzymes 2014; 36: 57-86. [ DOI:10.1016/B978-0-12-802215-3.00004-5] 18. Imenshahidi M, Razavi BM, Faal A, Gholampoor A, Mousavi SM, Hosseinzadeh H. Effects of crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats. Iran J Basic Med Sci 2014; 17: 9-13. 19. Jalili C, Tabatabaei H, Kakaberiei S, Roshankhah S, Salahshoor MR. Protective role of Crocin against nicotine-induced damages on male mice liver. Int J Prev Med 2015; 6: 92. [ DOI:10.4103/2008-7802.165203] 20. Salahshoor MR, Khashiadeh M, Roshankhah S, Kakabaraei S, Jalili C. Protective effect of crocin on liver toxicity induced by morphine. Res Pharm Sci 2016; 11: 120. 21. Modaresi M, Mesripour M, Asadi Margh Maleki M, Hamedanian MK. Effect of Saffron (Crocus Sativus) extract on level of FSH, LH and testosterone in mice. J Zanjan Univ Med Sci 2008; 16: 11-17. [In Persian] 22. Rafiee Z, Jalili F, Sohrabi M, Jalili C. Effects of hydro-alcoholic extract of falcaria vulgaris on pancreas tissue in streptozotocin-induced diabetic rats. Iran J Endocrinol Metab 2017; 19: 91-8. [In Persian] 23. Jalili C, Ahmadi S, Roshankhah S, Salahshoor M. Effect of Genistein on reproductive parameter and serum nitric oxide levels in morphine-treated mice. Int J Reprod Biomed 2016; 14: 95–102. [ DOI:10.29252/ijrm.14.2.95] 24. Peunova N, Enikolopov G. Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells. Nature 1993; 364: 450-3. [ DOI:10.1038/364450a0] 25. Lewis S, Donnelly E, Sterling E, Kennedy M, Thompson W, Chakravarthy U. Nitric oxide synthase and nitrite production in human spermatozoa: evidence that endogenous nitric oxide is beneficial to sperm motility. Mol Hum Reprod 1996; 2: 873-8. [ DOI:10.1093/molehr/2.11.873] 26. Roshankhah SH, Salahshoor MR, Jalili F, Karimi F, Sohrabi M, Jalili C. Crocin effects on the nicotine-induced ovary injuries in female rat. Int J Life Sci Pharma Res 2017; 7: 1-8. 27. Hellstrom WJ, Bell M, Wang R, Sikka SC. Effect of sodium nitroprusside on sperm motility, viability, and lipid peroxidation. Fertil Steril 1994; 61: 1117-22. [ DOI:10.1016/S0015-0282(16)56766-1] 28. Sengoku K, Tamate K, Yoshida T, Takaoka Y, Miyamoto T, Ishikawa M. Effects of low concentrations of nitric oxide on the zona pellucida binding ability of human spermatozoa. Fertil Steril 1998; 69: 522-7. [ DOI:10.1016/S0015-0282(97)00537-2] 29. Chen M, Dou J. Diabetes and gonadal disorders. JTIM 2014; 2: 119-23. 30. Bal R, Türk G, Tuzcu M, Yilmaz O, Ozercan I, Kuloglu T, et al. Protective effects of nanostructures of hydrated C 60 fullerene on reproductive function in streptozotocin-diabetic male rats. Toxicology 2011; 282: 69-81. [ DOI:10.1016/j.tox.2010.12.003] 31. Soerensen RR, Johannsen TH, Skakkebaek NE, Rajpert-De Meyts E. Leydig cell clustering and Reinke crystal distribution in relation to hormonal function in adult patients with testicular dysgenesis syndrome (TDS) including cryptorchidism. Hormones (Athens) 2016; 15: 518-26. [ DOI:10.14310/horm.2002.1708] 32. Samadi H, Javadi S, Asri S. Evaluation of the effects of crocin on the serum levels of glucose, insulin, urea, creatinine and β2m in healthy and streptozotocin-induced diabetic rats. Urmia Med J 2015; 26: 802-12. [In Persian] 33. Asadi MH, Zafari F, Sarveazad A, Abbasi M, Safa M, Koruji M, et al. Saffron improves epididymal sperm parameters in rats exposed to cadmium. Nephrourol Mon 2014; 6: 1-6. 34. Tarantilis PA, Polissiou M, Manfait M. Separation of picrocrocin, cis-trans-crocins and safranal of saffron using high-performance liquid chromatography with photodiode-array detection. J Chromatogr A 1994; 664: 55-61. [ DOI:10.1016/0021-9673(94)80628-4] 35. Duru NK, Morshedi M, Oehninger S. Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa. Fertil steril 2000; 74: 1200-7. [ DOI:10.1016/S0015-0282(00)01591-0] 36. Salahshoor MR, Khazaei M, Jalili C, Keivan M. Crocin improves damage induced by nicotine on a number of reproductive parameters in male mice. Int J Fertil Steril 2016; 10: 71-8.
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