[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
Webmail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Journal Citation Index

 

Citation Indices from GS

AllSince 2019
Citations89785395
h-index3725
i10-index235137

 

..
Central Library of Kurdistan University of Medical Sciences
AWT IMAGE
..
Vice-Chancellery for Research and Technology
AWT IMAGE
..
SCImago Journal & Country Rank
:: Volume 14, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2009) ::
SJKU 2009, 14(1): 55-64 Back to browse issues page
Study of the effect of lemon peel essential oil on blood lipid levels and differential leukocyte count
Parichehr Yaghmae 1, Kazem Parivar , Minoo Haftsavar , Farokh Zarebinan , Siroos Shahsavari
1- , Yaghmaei-P@yahoo.com
Abstract:   (13295 Views)
Background and Aim: Cardiovascular diseases are often the result of vessel occlusion by atherosclerosis and quantitative disturbances such as increased blood cholesterol and other plasma lipid levels, have important role in its pathogenesis. The most important cause of infectious diseases and its progress is insufficiency of immune system and especially insufficient activation of leukocytes. Therefore an increase in the number of leukocytes and augmentation of immune system can lead to prevention of infectious diseases. The aim of this research was to evaluate the effect of oral lemon peel essential oil on the level of blood lipids and differential leukocyte counts. Materials and Methods : In this research , one class of adult Wistar male rats were used (n=6), including control group that were fed with enough food and water, sham group and experimental groups (1,2,3) which were fed with %2 solution of cholesterol in oleic acid by gavage for five weeks. Simultaneously, lemon peel essential oil 25µLit/Kg, 50µLit/Kg and 100µLit/Kg were given to the first, second, and third experimental groups respectively, but sham group received saline solution. At the end of this period, blood samples were obtained from the heart ventricles of the rats to measure plasma lipids by enzymatic method, in control, sham and experimental groups. Blood smears were prepared to assess differential leukocyte counts. Data were introduced into SPSS (ver12) software and analyzed by means of Kruskul-walis and mann-whitney U statistical tests. Results: The results of this research showed that the effect of low doses of lemon peel essential oil was slight on decreasing the level of cholesterol and LDL in the experimental group in comparison to sham group (p<0.05) and had no significant effect on the level of triglyceride (p>0.05). However, moderate and high doses of the oil showed significant effects on decreasing cholesterol (p<0.01), LDL (p<0.01) and triglyceride levels (p<0.01). None of these doses resulted in significant effect on the plasma HDL (p>0.05). The study revealed that three doses of essential oil had significant effects on increasing the number of leukocytes (p<0.001). Conclusion: It is concluded that lemon peel essential oil probably can prevent atherosclerosis and decrease incidence of cardiovascular diseases by decreasing plasma lipid levels. In addition, it is likely lemon peel essential oil prevents infectious diseases and cancer by increasing the number of leukocytes and percentage of blood lymphocytes which result in augmentation of immune system. Conflict of Interest: Nill Received: Oct 17, 2008 Accepted: May 31, 2009
Keywords: Lemon peel essential oil, Blood lipids, Leukocyte, Rat, Wistar
Full-Text [PDF 155 kb]   (2793 Downloads)    
Type of Study: Original Research | Subject: General
Received: 2009/06/15 | Published: 2009/06/15
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Yaghmae P, Parivar K, Haftsavar M, Zarebinan F, Shahsavari S. Study of the effect of lemon peel essential oil on blood lipid levels and differential leukocyte count. SJKU 2009; 14 (1) :55-64
URL: http://sjku.muk.ac.ir/article-1-156-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 14, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2009) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 45 queries by YEKTAWEB 4645