ABSTRACT

Background and Aim: Exosomes are small vesicles that carry molecules like miRNA, mRNA, and proteins. They are released by various types of cells and play a vital role in intercellular communication, material transfer, and regulation of cell function.
Materials and Methods: Our research involved searching the PubMed and Scopus data centers, collecting data from various articles, and comparing them to write this article.
Results: Exosomes secreted by regenerative medicine cells are responsible for the healing and regeneration properties. Using cells in cell therapy triggers the recipient's immune system and poses significant risks. A new project in cell therapy, called cell-free therapy, involves using exosomes instead of cells, reducing the risk of rejection of transplanted cells and is a more cost-effective approach.
Conclusion: Exosomes can change gene expression and accelerate tissue regeneration. They are widely used in tissue engineering and cell therapy and have the potential to be a future horizon in regenerative medicine