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:: Volume 29, Issue 6 (Scientific Journal of Kurdistan University of Medical Sciences 2025) ::
SJKU 2025, 29(6): 64-76 Back to browse issues page
Comparison of the Diagnostic Value of Fine Needle Aspiration and Frozen Section in Patients with Thyroid Nodule Surgery Referring to Babol University of Medical Sciences Hospitals between 2011 and 2019
Novin Nikbakhsh1 , Amir Morteza Rezazadeh2 , Ali Bijani3 , Sekineh Kamali Ahangar4 , Mohammad Rnaee5
1- Professor of Thoracic Surgery, Department of Surgery, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran & Professor of Thoracic Surgery, Department of Surgery, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
2- Student of General Medicine, Student Research Committee, Babol University of Medical Sciences, Babol, Iran & Student of General Medicine, Student Research Committee, Babol University of Medical Sciences, Babol, Iran
3- . Associate Professor of Epidemiology, Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran & . Associate Professor of Epidemiology, Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
4- Midwifery Expert, Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran & Midwifery Expert, Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran
5- Associate Professor of Pathology, Clinical Research Development Unit of Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran & Associate Professor of Pathology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran , drm.ranaee@yahoo.com
Abstract:   (640 Views)

Background and Aim: Thyroid nodules are among common clinical problems and fine needle aspiration (FNA) sampling is the most important method to diagnose its pathological nature. The frozen section (FS) is also very important in making treatment decisions. The present study was conducted to compare the diagnostic value of these two methods based on pathology findings in the patients with thyroid nodules.
Materials and Methods: This descriptive-analytical study included patients with thyroid nodule surgery between 2011 and 2019 in Babol City. Information was collected by file reading method. Data analysis was done using SPSS-26 software and a comparative survey of the diagnostic value of pathology methods, FNA biopsy, and FS examination, was performed by calculating the sensitivity, specificity, and positive and negative predictive value (p<0.05).
Results: The majority of patients in this study were female (68.66%) and the patients did not have any family history (70.44%). In the final pathology findings, the rates of benign and malignant lesions were; 54.88% and 45.11%, and in FNA and FS, they were 67% and 88.57%, respectively. Sensitivity, specificity, positive and negative predictive values in FNA were; 0.9582, 0.9896, 0.9950, and 0.9697, respectively. Sensitivity, specificity, positive and negative predictive value in FS were 100%. The two mentioned methods were consistent in 58.8% of the cases in the diagnosis of malignant or benign thyroid nodules (p<0.001).
Conclusions: FNA is a reliable method for detecting malignancy in thyroid nodules due to its high sensitivity and specificity. On the other hand, the FS is considered a precise method due to its high correlation with pathology.

 
Keywords: Diagnostic value, Fine needle aspiration, Frozen section, Thyroid nodule
Full-Text [PDF 668 kb]   (97 Downloads)    
Type of Study: Original Research | Subject: Medicine - General Surgery
Received: 2022/08/23 | Accepted: 2023/07/31 | Published: 2025/03/9
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Nikbakhsh N, Rezazadeh A M, Bijani A, Kamali Ahangar S, Rnaee M. Comparison of the Diagnostic Value of Fine Needle Aspiration and Frozen Section in Patients with Thyroid Nodule Surgery Referring to Babol University of Medical Sciences Hospitals between 2011 and 2019. SJKU 2025; 29 (6) :64-76
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Volume 29, Issue 6 (Scientific Journal of Kurdistan University of Medical Sciences 2025) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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