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:: Scientific Journal of Kurdistan University of Medical Sciences - No 3, 2022 ::
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Prevalence and antimicrobial resistance pattern of isolated pathogens among patients with nosocomial infections in intensive care units of Hazrat-e Rasool General Hospital, Tehran, 2020
Omid MoradiMoghaddam1 , , Mohammad Azad Majedi2 , Khaled Rahmani3 , Mohammad Niakan Lahiji4 , Sara Minaeian 5
1- Assistant Professor of Critical Care Medicine, Department of Anesthesiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
2- Subspeciality of ICU, Department of Anesthesiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
3- Assistant Professor of Epidemiology, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
4- Assistant Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5- Assistant Professor of Microbiology, Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran , sara.minaeian@gmail.com
Abstract:   (80 Views)
Background and Aim: Nosocomial infections, the pathogens that cause these infections, and the antibiotic resistance of these agents have always been one of the concerns of the health system. The aim of this study was to determine the frequency of each of the pathogens causing nosocomial infections and their antimicrobial resistance in patients admitted to the intensive care units of a general hospital.
Materials and Methods: This cross-sectional study was performed on 936 biological samples of patients admitted to the intensive care units of Hazrat-e Rasool general hospital in Tehran in 2020. After determining the frequency of pathogens isolated from the samples using specific differential culture media and specific antisera, disk diffusion method was used to determine the antibiotic resistance of the most common bacterial agents causing nosocomial infections.
Results: Acinetobacter (22.5%), Klebsiella pneumoniae (18.7%), Pseudomonas aeruginosa (13.6%), Candida albicans (11.2%) and Escherichia coli (7.2%), respectively, were the most common pathogens of nosocomial infections in the studied samples.
Acinetobacter isolates which were the most common pathogen causing nosocomial infections in this study, were most sensitive to the antibiotics Clostin (100%) and cefotaxime (97.2%), respectively. The most resistant antibiotic against Acinetobacter isolates was the antibiotic Ampicillin Sulbactam (38.9%) .
Conclusion: The results of the present study showed that in addition to the diversity of different pathogens in causing nosocomial infections in patients admitted to intensive care units, antibiotic resistance of these factors is also significant. It is necessary to pay attention to periodic studies to monitor antibiotic resistance in the treatment of nosocomial infections, especially in intensive care units.
Keywords: Nosocomial infection, antibiotic resistance, intensive care unit
     
Type of Study: Original Research | Subject: Microbiology
Received: 2021/04/26 | Accepted: 2021/07/25
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Ethics code: IR.IUMS.FMD.REC.1399.887


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مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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