[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Scientific Journal of Kurdistan University of Medical Sciences - No 2, 2022 ::
Back to the articles list Back to browse issues page
Association between Serum Omentin-1 Level with Insulin Resistance, ‎Hematological Factors and Fetal Week Length in Preterm Infants ‎
Nahideh Tahmasebpour Shahsavar1 , Fariba Pishbin1 , Monireh Taghizadeh , Roghayeh Shahabi , Somayeh sadat Heidari1
1- Department of Clinical Biochemistry, Hamadan University of Medical Sciences; Hamadan, Iran ‎
Abstract:   (97 Views)
Background and Aim: Premature birth is one of the most important causes of mortality in the world and is one of the major health problems. In this study, we investigated the relationship between the serum levels of omentin-1with insulin resistance and inflammatory markers in preterm infants.
Material and Methods: The study was performed on 32 preterm and 21 full term newborns. The serum levels of insulin and omentin-1 were measured by ELISA. Fasting blood glucose and C-reactive protein (CRP) were measured with an AutoAnalyzer. Hematological parameters were measured by Sysmex.
Results: Serum omentin-1(p<0.001) was lower, while insulin levels (p = 0.002) and insulin resistance (p=0.011) were significantly higher in preterm infants than full term infants. Hematologic parameters were not significantly different between the two groups. The serum C-reactive protein (CRP) levels were significantly higher in preterm infants than term infants (p<0.001). Omentin-1 levels in preterm infants were negatively correlated with platelet and white blood cell counts (r =-0.308 and r =-0.306, respectively). The serum omentin-1 level was positively and significantly correlated with fetal week length in preterm infants (r=0.344 and p=0.012), Insulin resistance was significantly higher in preterm infants than in preterm infants (p=0.011). The serum omentin-1 level had a significant negative correlation with the serum insulin levels and insulin resistance (r= 0.362 and r=0.229).
Conclusion: Serum omentin-1 in preterm infants was lower and negatively correlated with inflammatory factors and insulin resistance, and positively with fetal week length.
Keywords: omentin-1, insulin, CRP, preterm infants‎
     
Type of Study: Original Research | Subject: Biochemistry and Clinical Laboratory
Received: 2021/01/28 | Accepted: 2021/08/3
Add your comments about this article
Your username or Email:

CAPTCHA

Ethics code: IR.UMSHA.REC.1396.915‎


XML   Persian Abstract   Print



Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Back to the articles list Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4343