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:: Volume 27, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2022) ::
SJKU 2022, 27(3): 129-134 Back to browse issues page
Rapid and Progressive Transformation of Well-Differentiated Retroperitoneal Liposarcoma to Poorly Differentiated Type: A Case Report
Mehdi Kardoust Parizi 1, Mohammad mehdi Miri2
1- Department of urology, School of medicine, Tehran university of medical sciences, Tehran, Iran , m.kardoust@yahoo.com
2- Department of urology, School of medicine, Tehran university of medical sciences, Tehran, Iran
Abstract:   (1305 Views)
Background and Aim: Retroperitoneal liposarcoma (LS) is a rare neoplasm. Well-differentiated LS is a slow-growing subtype with a high rate of recurrence. Despite the high recurrence rate after complete surgical resection, tumor transformation to poorly-differentiated LS is very rare.
Case:  A 45-year-old man with a primary retroperitoneal tumor and the final pathology of well-differentiated LS underwent tumor resection surgery. Local recurrence was detected nine months after surgery. Second surgical resection revealed a poorly-differentiated subtype of LS which was treated with adjuvant radiation therapy. No local recurrence and distant metastasis were detected in a three years follow-up period.
Conclusion: Tumor transformation of well-differentiated retroperitoneal LS to poorly-differentiated subtype is extremely rare. Nevertheless, this rare case was successfully managed in a multi-disciplinary setting using surgical resection and adjuvant radiation therapy.
 
Keywords: Liposarcoma, Retroperitoneal Sarcoma, Retroperitoneal Tumor, Radiation Therapy.
Full-Text [PDF 246 kb]   (287 Downloads)    
Type of Study: case report | Subject: Medicine - Urology
Received: 2020/07/24 | Accepted: 2021/07/14 | Published: 2022/09/11
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Kardoust Parizi M, Miri M M. Rapid and Progressive Transformation of Well-Differentiated Retroperitoneal Liposarcoma to Poorly Differentiated Type: A Case Report. SJKU 2022; 27 (3) :129-134
URL: http://sjku.muk.ac.ir/article-1-6191-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 27, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2022) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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