Background and Aim: The commonest presentation in Hodgkin`s disease is painless cervical lymphadenopathy with or without a mediastinal mass. Uncommon presentations of Hodgkin`s disease that has been so far reported include: spinal cord compression, localized poikiloderma vascularis atrophicans, unilateral lower extremity lymphedema, multifocal nodular episcleritis and scleritis, Immune thrombocytopenia and hemolytic anemia, granolomatous keratoconjunctivitis, subdiaphragmatic Hodgkin`s disease. In these cases uncommon presentations were extramediastinal.
Case Report: In this case Hodgkin’s disease presented with right lung middle lobe syndrome without hillar or mediastinal lymphadenopathy. CT guided needle biopsy of pulmonary lesion revealed Hodgkin`s disease and response to chemotherapy was very good.
Conclusion: The typical presentation of pulmonary Hodgkin`s disease includes multiple, irregularly marginated pulmonary nodules in the hillar or mediastinal areas. Our case had an uncommon presentation of pulmonary Hodgkin`s disease. Therefore for early diagnosis and treatment, such presentations of the disease should be taken into consideration.
Baygom Mir Behbahani N. Right lung middle lobe syndrome as the initial and sole clinical manifestation of Hodgkin’s disease. SJKU 2007; 12 (1) :66-69 URL: http://sjku.muk.ac.ir/article-1-112-en.html