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Correlation between iron deficiency anemia and febrile convulsion
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Parsa Yousefi1   , Aziz Eghbali1 , Mohammad Rafeie1 , Mohaddeseh Zolfi 2, Mohammad Reza Firouzifar1 |
1- Arak University of Medical Sciences
2- Arak University of Medical Sciences , dr.firouzifar@arakmu.ac.ir |
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Abstract: (15258 Views) |
| ABSTRACT
Background and Aim: Febrile convulsion is the most common neurological disease of childhood. Regarding the current hypotheses about possible effect of iron deficiency on prevention of febrile convulsion and its relationship to neuronal stimulation threshold, we conducted this study to evaluate the relationship between iron deficiency anemia and simple febrile convulsion.
Materials and methods: In this case-control study, 382 children who met our inclusion criteria and had been admitted in Arak Amirkabir Hospital were assigned to two groups: case (with febrile convulsion) and control (other febrile diseases). After the fever subsided, a 5 cc sample of blood was taken from every patient for complete blood count and iron reserve profile. The results were analyzed by using descriptive statistics and independent t-test.
Results: Iron deficiency anemia was significantly less frequent in our case group compared to the control group (22.5% vs. 34.0%) (p<0.001). CBC indices such as Hb, HCT, MCV, MCH and MCHC were significantly (p<0.001) higher in the case group in comparison to the control group.
Conclusion: Iron deficiency can prevent the febrile convulsion probably by increasing neuronal excitation threshold.
Conflict of Interest: Nil
Received: May 16, 2012 Accepted: Apr7, 2013 |
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| Keywords: Febrile convulsion, Iron deficiency anemia, Children |
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Full-Text [PDF 328 kb]
(8777 Downloads)
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Type of Study: Original Research |
Subject:
General
Received: 2013/06/18 | Accepted: 2013/06/18 | Published: 2013/06/18
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