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Prevalence, Resistance Pattern, and Clinical Outcomes of Klebsiella pneumoniae in the Intensive Care Unit of Kowsar Hospital, Sanandaj in 2023
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Behzad Ahsan1    , Qazal Ghaderi2 , Mohammad Emami1 , Khaled Rahmani3 , Mohammad azad Majedi4 |
1- Department of Anesthesiology, Kurdistan University of Medical Science & Kurdistan University of Medical Science
2- Student Research Committee & Iran university of medical science
3- Department of Family and Community Medicine & Kurdistan University of Medical Science
4- Department of Anesthesiology, Kurdistan University of Medical Science & Kurdistan University of Medical Science , aa136020062007@yahoo.com |
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Abstract: (121 Views) |
Background and Aim:
Klebsiella pneumoniae is an important opportunistic pathogen in hospital-acquired infections, which is associated with a significant increase in complications, especially in intensive care units (ICUs). The global rise in multidrug resistance (MDR) of this bacterium, including carbapenem-resistant Klebsiella pneumoniae (CRKP) strains, has made clinical management a serious challenge. This study was conducted to investigate the prevalence, resistance pattern, and clinical outcomes of Klebsiella pneumoniae in the intensive care unit of Kosar Hospital, Sanandaj 2023.
Materials and Methods:
This retrospective cohort study was performed on the records of 262 patients admitted to the ICU of Kosar Hospital during the year 2023. Information including demographic characteristics, length of hospital stay, cause of admission, sources of microbial culture, and clinical outcomes of patients was collected using a checklist and analyzed using SPSS softwareversion 24.
Results:
The results showed that 155 patients (59.2%) were infected with Klebsiella pneumoniae. The mean age of the patients was 57.35 ± 22.13 years, and 67.6% (177 individuals) were male. The most common causes of admission were cerebral infarction (24%) and multiple trauma (20.2%). In addition, the main source of microbial culture samples was tracheal secretions (49.6%). Statistical corelation analysis showed a significant association between Klebsiella pneumoniae infection and patients’ clinical outcomes (p = 0.042) as well as the length of hospital stay (p = 0.004).
Conclusion:
This study demonstrated a high prevalence of Klebsiella pneumoniae infection in the intensive care unit, which was associated with increased mortality and prolonged hospitalization. These findings highlight the importance of strict infection control, particularly regarding the use of invasive devices such as mechanical ventilators. The results of this research are consistent with global observations and emphasize the necessity of improving prevention and management strategies for multidrug-resistant infections.
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| Keywords: Healthcare-Associated Infection, Klebsiella pneumoniae, Intensive Care Unit (ICU), Drug Resistance |
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Type of Study: Original Research |
Subject:
Medicine - Infectious
Received: 2025/10/5 | Accepted: 2026/01/25
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