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A Case Report of Ganglioneuroblastoma with Non-Specific Presentations: Diagnostic and Management Challenges
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Mahmoud Khodabandeh1    , Farzad Kompani2 , Fariba Fashandaky2 , Mohammadsadegh Talebi Kahdouei2 , Katayoun Borhani2 , Hamid Eshaghi2 |
1- Tehran University of Medical Sciences , khodabandeh@farabi.tums.ac.ir
2- Tehran University of Medical Sciences |
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Abstract: (12 Views) |
Background: Ganglioneuroblastoma is a rare tumor with a diverse clinical presentation, often leading to a delay in diagnosis due to nonspecific symptoms. GNB originates from neural crest cells and usually presents in early childhood. Given the diverse presentation of the patient, it can pose a diagnostic challenge. We report a case of GNB that was initially misdiagnosed as septic arthritis.
Case presentation: The case was a 25-month-old boy who presented with fever, limping, and pelvic pain and was initially diagnosed as septic arthritis. Due to the lack of response to antibiotic therapy, further investigation led to the diagnosis of metastatic GNB.
Conclusion: This case highlights the importance of considering malignancies in the differential diagnosis of musculoskeletal symptoms in children who fail to respond to initial treatment. It also highlights the critical role of advanced imaging and biopsy in reaching a definitive diagnosis.
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| Keywords: Neuroblastoma, Septic arthritis, Malignant, Infectious. |
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Type of Study: case report |
Subject:
Medicine - Pediatric
Received: 2025/04/27 | Accepted: 2025/11/11
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