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:: Volume 20, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2015) ::
SJKU 2015, 20(3): 86-93 Back to browse issues page
Investigatation of diagnostic value of random urine protein/creatinine ratio in pre-eclampsia
Farnaz Zandvakili Dr, Sara Matini Dr, Ezatollah Rahimi Dr 1, Shoaleh Shahgheibi Dr, Ebrahim Ghaderi Dr, Naser Reshadmanesh
1- , e_rahimi258@hotmail.com
Abstract:   (2935 Views)
Background and Aim: Standard diagnostic procedure for significant proteinuria is based on 24-hour urine collection. However, this method is time consuming and may lead to incomplete urine collection. Instead, random urine protein/creatinine ratio could be used as an alternative method for evaluation of proteinuria. This study investigates the diagnostic value of random urine protein/creatinine ratio for the diagnosis of pre-eclampsia. Material and Methods: In this cross-sectional study a group of 96 patients with pre-eclampsia and a group of healthy pregnant women were recruited. All cases were checked for urine protein by assessing urine analysis, 24-hour urine, and random urine protein/creatinine ratio. Data were analyzed using SPSS and ROC curve. Then a cutoff point of random urine protein/ creatinine ratio was determined. Results: Area under the curve for random Pr/Cr was calculated as 0.785 (CI %95: 0.721-0.849) (p<0.001). The best diagnostic cutoff point for protein/creatinine ratio was determined as 0.325. In this point sensitivity and specificity were 81.3% and 66.7% respectively. As a result, a positive correlation between random urine protein/creatinine ratio and systolic blood pressure (r = 0.284, p = 0.005) was observed. Conclusion: Based on these results, random urine protein/creatinine ratio in a cutoff point of 0.325 could be suggested for preeclampsia. Keywords: Preeclampsia, Proteinuria, Diagnosis. Received: Oct 19, 2014 Accepted: Feb 24, 2015
Keywords: Preeclampsia, Proteinuria, Diagnosis.
Full-Text [PDF 336 kb]   (3191 Downloads)    
Type of Study: Research | Subject: General
Received: 2015/07/12 | Accepted: 2015/07/12 | Published: 2015/07/12
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Zandvakili F, Matini S, Rahimi E, Shahgheibi S, Ghaderi E, Reshadmanesh N. Investigatation of diagnostic value of random urine protein/creatinine ratio in pre-eclampsia. SJKU. 2015; 20 (3) :86-93
URL: http://sjku.muk.ac.ir/article-1-1852-en.html


Volume 20, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2015) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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