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:: Volume 18, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2013) ::
SJKU 2013, 18(3): 104-111 Back to browse issues page
Evaluation of the validity of two hemoglobinometry methods for measurement of hemoglobin levels in whole blood donors in Yazd, 2010-2011
Haideh Javadzadeh Shahshahani Dr 1, Hosein Taymori Dr2, Nahid Akbari Dr3, Mahtab Vaziri Dr4, Nahid Meraat Dr4, Farahnaz Amiri Dr4
1- Assistant Professor Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine , hjavadzadeh@yazdbto.ir
2- Assistant Professor Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine
3- Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Esfahan
4- Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Yazd
Abstract:   (7014 Views)
ABSTRACT Background and aim: Hemoglobin screening methods before blood donation need to be not only simple, rapid and inexpensive but also sensitive for detection of both low and high hemoglobin levels to prevent false rejection of potential donors. The aim of this study was to evaluate the validity of two methods of hemoglobinometry in blood donors. Material and Method: In this cross sectional study, 198 blood donors were randomly selected. The hemoglobin levels of two blood samples taken by means of a single finger stick were determined by Hemocue 201+ and Hemocontrol and hemoglobin level of a venous blood sample was measured by Cobas hematology analyzer as standard method. Venous hemoglobin range of 12.5-17.9 g/dl was regarded as inclusion criteria for blood donation. The sensitivity, specificity and correlation between reference method and each of the hemoglobinometers were assessed. Data analysis was performed by means of correlation tests, regression analysis and paired t-test. Results: Mean hemoglobin levels measured by Cobas, Hemocue and Hemocontrol were 15.9±1.68, 16.28±1.91 and 16.30±196 g/dl, respectively. Hemoglobin levels measured by hemoglobinometers were higher than that measured by the standard reference. This difference was not significant in low hemoglobin levels, contrary to high hemoglobin levels. Each of the two methods showed significant correlation with standard method when hemoglobin levels were lower than normal limit. Increased hemoglobin levels led to decreased correlation coefficient which was not significant with hemoglobin levels higher than 18g/dl. Conclusion: Our study results showed that these heomoglobinometers were not valid for screening high hemoglobin levels in blood donors and a large number of potential donors would be falsely rejected. Further studies to find valid methods are recommended. Key words: Validity, Hemoglobin, Sensitivity, Specificity, Blood donors. Received: Aug 5, 2012 Accepted: Jun 18, 2013 Conflict of interest: None declared
Keywords: Validity, Hemoglobin, Sensitivity, Specificity, Blood donors.
Full-Text [PDF 231 kb]   (1059 Downloads)    
Type of Study: Research | Subject: General
Received: 2013/10/4
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Volume 18, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2013) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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