Assistant Professor, Department of Infectious Diseases, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran , glotfi12340@gmail.com
Abstract: (177 Views)
Background and Aim:Brucellosis is one of the most prevalent zoonotic infections in endemic regions, presenting with a wide spectrum of clinical features, ranging from nonspecific systemic symptoms to multi-organ involvement, most commonly affecting the osteoarticular system. Soft tissue abscesses are a rare presentation of brucellosis and may delay diagnosis. Case Presentation: We present the case of a 39-year-old male livestock farmer from a rural area who developed progressive pain and swelling in the posterior aspect of the left calf. Physical examination revealed a tender, warm swelling. Laboratory investigations showed relative lymphocytosis and elevated inflammatory markers, including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Serological tests, including Wright, Coombs Wright, and 2-mercaptoethanol (2ME) tests, were strongly positive, consistent with active brucellosis. Magnetic resonance imaging revealed a well-defined fluid collection in the posterior compartment of the calf, consistent with an intramuscular abscess. Aspiration of the lesion confirmed the presence of Brucella species. The patient was treated with a three-drug regimen of doxycycline, rifampin, and gentamicin, followed by an extended eight-week oral regimen of doxycycline and rifampin. At the two-month follow-up, the patient had achieved complete clinical recovery, with normalization of serological titers. Conclusion: This case highlights the importance of considering brucellosis in the differential diagnosis of unusual soft tissue abscesses, particularly in endemic areas.