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Comparison of BrucellacapT Sensitivity and Specificity with Standard Wright Tube Agglutination Test in The Diagnosis of Brucella
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Hamid Reza Ghasemi Basir1  , Mohammad Mahdi Majzoobi2 , Abbas Moradi3 , Sadi Hesami Novin4 , Ali Saadatmand 5 |
1- Associate Professor, Department of Pathology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2- Associate Professor, Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
3- MSc in Epidemiology, Department of community medicine, school of medicine, Hamadan University of Medical Sciences, Hamadan, Iran
4- General Practitioner, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
5- MSc in Microbiology, Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran , Ali.s_umsha@yahoo.com |
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Abstract: (480 Views) |
Background and Aim: Brucellosis is one of the most common infectious diseases between humans and livestock in Iran. Because of the diagnostic problems of brucellosis, especially in endemic areas, the use of new diagnostic methods is of great importance. Therefore, this study was performed to compare BrucellacapT sensitivity and specificity with the standard Wright tube agglutination test in the diagnosis of Brucella.
Materials and Methods: A total of 100 sera from a patient with suspected symptoms of brucellosis and without laboratory confirmation were studied. Wright, Coombs wright, and BrucellacapT tests were performed at diagnostic threshold titers of 1.160 and 1.80 Sensitivity, specificity, and positive and negative predictive values were evaluated and finally, data were analyzed with SPSS software version 14.
Results: A total of 100 patients were included in the study, of which 45% were female and 55% were male. In titrate 1.160 positive Wright test as a diagnostic threshold, sensitivity, specificity, and positive and negative predictive values for the BrucellacapT test were 97.95, 86.27, 87.27, and 97.97 percent, respectively. In titrate 1.80 positive Wright test as a diagnostic threshold, sensitivity, specificity, and positive and negative predictive values of BrucellacapT test were 98.43, 97.50, 95.45, and 97.05 percent, respectively.
Conclusion: The results showed that the BrucellacapT test in the studied cut points has acceptable sensitivity, specificity, and positive and negative predictive value for the diagnosis of brucellosis and the diagnostic and accuracy of this test in the titrate 1.160 is very close to the Coombs Wright test.
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| Keywords: Brucellosis, Wright, Coombs Wright, BrucellacapT |
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Full-Text [PDF 532 kb]
(136 Downloads)
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Type of Study: Original Research |
Subject:
Microbiology
Received: 2022/01/12 | Accepted: 2022/04/10 | Published: 2023/03/15
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Ethics code: IR.UMSHA.REC.1399.174
Ghasemi Basir H R, Majzoobi M M, Moradi A, Hesami Novin S, Saadatmand A. Comparison of BrucellacapT Sensitivity and Specificity with Standard Wright Tube Agglutination Test in The Diagnosis of Brucella. SJKU 2023; 28 (1) :65-73 URL: http://sjku.muk.ac.ir/article-1-7180-en.html
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