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New Epidemiological Feature of Cutaneous Leishmaniasis in an Endemic Focus in Golestan Province
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Yousef Moghaddam1    , Hajar Ziaei Hezarjaribi 2, Mahdi Fakhar3 , Abdol Sattar Pagheh4 , Reza Saberi1 , Eisa Nazar5 , Mitra Sharbatkhori6 , Hossein Ghalehnoei7 |
1- Ph.D. Candidate in Parasitology, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
2- Assistant professor, Pediatric infectious Disease Research Center, Communicable Disease Institute, Department of Parasitology School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran , ziaei2000@yahoo.com
3- Professor, Toxoplasmosis Research Center, Communicable Diseases Institute, Iranian National Registry Center for Lophomoniasis and Toxoplasmosis, Department of Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
4- Assistant Professor, Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
5- Ph.D. Candidate in Biostatistics, Student Research Committee, Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
6- Associate Professor, Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
7- Assistant Professor of Molecular Medicine Department of Medical Biotechnology, School of Advanced Technologies in Medicine Molecular and Cell Biology Research Center, Mazandaran, Iran |
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Abstract: (2329 Views) |
Background and Aim: Cutaneous leishmaniasis (CL) is an important health problem in Iran and one of the world ̛s neglected diseases which is caused by Leishmania spp. The aim of this study was to investigate the epidemiology of cutaneous leishmaniasis and its associated risk factors in an endemic center in Golestan Province.
Materials and Methods: This descriptive cross-sectional study included patients with suspected CL who had been referring to the health centers of Gonbad–e Qabus town, between 2018 and 2020. Demographic and epidemiological data of CL patients were recorded and diagnosis of Leishmania spp. was made by Giemsa staining of direct smear. PCR was also used to determine and confirm the parasite species.
Results: From 1979 suspected CL lesions, 1704(87.4%) had positive smears. 898 (52.7%) patients were male and 806 (47.3%) were female. The highest incidence rate was observed in the patients of less than 5 (25.93%) and those between 25 and 45 years of age (25.41%). In all samples in this study, Leishmania major was the only Leishmania spp detected by ITS-PCR. Also, Critidia fasciulata was identified in three patients.
Conclusion: The study provided valuable data concerning the epidemiologic aspects of the CL in an old endemic focus in north of Iran, which can be used as the basis for planning future control strategies.
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| Keywords: Cutaneous leishmaniasis, Epidemiology, PCR, Crithidia, Gonbad–e Qabus |
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Full-Text [PDF 491 kb]
(616 Downloads)
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Type of Study: Original Research |
Subject:
Parasitology and Mycology
Received: 2021/02/7 | Accepted: 2021/09/1 | Published: 2022/09/11
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Ethics code: 1719
Moghaddam Y, Ziaei Hezarjaribi H, Fakhar M, Pagheh A S, Saberi R, Nazar E, et al . New Epidemiological Feature of Cutaneous Leishmaniasis in an Endemic Focus in Golestan Province. SJKU 2022; 27 (3) :77-88 URL: http://sjku.muk.ac.ir/article-1-6585-en.html
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