[Home ] [Archive]   [ فارسی ]  
:: Volume 24, Issue 4 ( Scientific Journal of Kurdistan University of Medical Sciences 2019) ::
SJKU 2019, 24(4): 95-102 Back to browse issues page
Prevalence of gallstone disease in the patients with non-alcoholic fatty liver disease (NAFLD) in Sanandaj: A case control study
Karim Sharifi1 , Nima Fattahi2 , Zakaria Vahabzadeh3 , Pedram Ataee4 , Vahid Yousefinejad5 , Asrin Babahajian6 , Farshad Sheikhesmaili 7
1- Assistant Professor of Radiology, Department of Radiology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
2- General Practitioner, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
3- Assistant Professor of Clinical Biochemistry, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
4- Assistant Professor of Liver and Digestive Diseases, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
5- Assistant Professor of Forensic Medicine, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
6- MSc of Anatomical Science, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
7- Assistant Professor of Liver and Digestive Diseases, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran. , Dr_S_Smaili@yahoo.com
Abstract:   (248 Views)
Background and Aim: Nonalcoholic fatty liver disease (NAFLD) and gallstone disease (GD) are both highly prevalent in the general population and have many risk factors in common. The aim of this study was to evaluate the prevalence of GD in the patients with NAFLD.
Materials and Methods: In this case-control study, our case group included 145 patients with NAFLD and control group consisted of 215 age-, sex-, and BMI-matched healthy subjects. NAFLD and gallstone disease were diagnosed by sonography. The prevalence and risk factors for gallstone disease were evaluated in the groups and compared between the 2 groups.
Results: The frequency rates of gallstones in the case and control groups were 10/135 (6.9 %) and 5/210 (2.3 %) respectively (p=0.04). The frequency rates of gallstones in the female participants in the case and control groups were 6.8% and 3.4%, respectively, and in the men were 6.9% in the case and 1% in the control groups. We found no significant relationship between sex and frequency of gallstones in both groups (P> 0.05). In the control group, the prevalence rate of GD in the subjects over 50 years of age were significantly higher than that in the subjects under 50 years of age (P = 0.04). However, there was no significant difference between ag e and GD in the case group (P = 0.51). Also, in both groups, the prevalence of GD was significantly higher in obese subjects (BMI> 30) (P> 0.05). There was a significant difference between the grade of fatty liver and the prevalence of GD (P = 0.01). Comparison of the risk factors associated with the GD, showed no significant difference between the two groups.
Conclusion: The prevalence of gallstones was more in NAFLD than in normal population and was associated with grade of fatty liver disease.
Keywords: Gallstones, Non-alcoholic fatty liver disease, Ultrasound, Risk factors
Full-Text [PDF 251 kb]   (59 Downloads)    
Type of Study: Research | Subject: General
Received: 2019/01/26 | Accepted: 2019/07/7
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sharifi K, Fattahi N, Vahabzadeh Z, Ataee P, Yousefinejad V, Babahajian A et al . Prevalence of gallstone disease in the patients with non-alcoholic fatty liver disease (NAFLD) in Sanandaj: A case control study. SJKU. 2019; 24 (4) :95-102
URL: http://sjku.muk.ac.ir/article-1-4749-en.html


Volume 24, Issue 4 ( Scientific Journal of Kurdistan University of Medical Sciences 2019) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
Persian site map - English site map - Created in 0.06 seconds with 31 queries by YEKTAWEB 4006