Background and Aim: Increase in some inflammatory factors secreted by the adipose tissue can have predisposing effect on the development of metabolic syndrome. This study aimed to assess the effect of 12 weeks of aerobic training on serum levels interleukin-6, vaspin and serum amyloid A in postmenopausal women with metabolic syndrome. 

Material and Methods: In this semi-experimental study, 30 postmenopausal women with metabolic syndrome (mean age: 61 ± 9.48 years, body mass index: 32.16± 6.23 Kg/m2, and body fat: 30.82 ± 2.71%) were assigned to two experimental and control groups. The experimental group performed 12 weeks of aerobic training (3 sessions per week, with an intensity of 65-75% of maximum oxygen consumption at the first session which increased to 75-85 percent of maximum oxygen consuming) . 24 hours before and 48 hours after the last training sessions, blood samples were obtained and body fat percentage was measured. Data were analyzed by using independent and paired t-tests and also Pearson's correlation coefficients. P<0.05 was considered significant. 

Results: We found significant decrease in the serum levels of interleukin-6, vaspin and serum amyloid A (P values  were 0.0001, 0.01, 0.04 respectively) and fat percentage (P=0.02) in the experimental group. No significant changes were observed in the control group. There was a significant  positive correlation between the mean body fat and serum levels of  interleukin-6, vaspin and serum amyloid A (P<0.05).

Conclusion: It seems that aerobic training can be effective in reducing inflammatory conditions by decreasing inflammatory factors in the patients with  metabolic syndrome.

Keywords: Aerobic training, Interleukin -6, Vaspin, Serum amyloid A, Postmenopausal women, Metabolic syndrome.

Received: May 17, 2016      Accepted: Sep 28, 2016