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:: Volume 21, Number 3 (Scientific Journal of Kurdistan University of Medical Sciences 2016) ::
SJKU 2016, 21(3): 79-88 Back to browse issues page
The effect of endurance training on serum adhesion molecules in overweight men
Dr Hojatollah Nikbakht1, Dr Abasali Gaeini2, Khalid Mohammadzadeh Salamat 3
1- Associate Professor Department of Exercise Physiology, Islamic Azad University, Science and Research Branch, Tehran, Iran
2- Professor Faculty of Physical Education and Sport Sciences, Tehran University, Tehran, Iran
3- Faculty of Literature and Human Sciences, Islamic Azad University, Science and Research Branch, Tehran, Iran,(Corresponding Author), Tel:+98-8733660198 , kh.mohammadzadeh@gmail.com
Abstract:  

Background and Aim: Cell adhesion molecules are glycoproteins that mediate leukocyte response to inflammation. Increased level of these molecules may be directly associated with metabolic and cardiovascular diseases. The purpose of this study was to evaluate the effect of endurance training on serum adhesion molecules in overweight men.

Materials and Methods: Twenty two overweight students (BMI=28.34 kg/m2) voluntarily participated in this study. They were randomly divided into two groups, endurance training (n = 11) and control (n=11). Training group participants accomplished 3 sessions of endurance training program for 8 weeks. Before and after every exercise, fasting blood samples were taken from all the subjects and serum levels of soluble intercellular adhesion molecule-1(sICAM-1), soluble vascular adhesion molecule-1(sVCAM-1) and soluble E-selectin were measured. Data were analyzed by repeated measure ANOVA test.

Results: Data showed significant differences in the levels of sICAM-1 between the groups after eight weeks of endurance training (P=0.002). Comparison of the  groups’ pre- and post exercise mean values of the levels of sICAM-1 showed significant changes in endurance group (P=0.001). Serum levels of sVCAM-1 and soluble E selectin showed no significant changes (p>0.05).

Conclusion: According to the results we can conclude that endurance training can decrease the levels of some of adhesion molecules. It could be responsible, to some extent for possible reduction of systemic inflammation, caused by physical activity.

Keywords: Cell adhesion molecules, Exercise, Overweight.

Received: Jan 25, 2016      Accepted: Apr 6, 2016

Keywords: Cell adhesion molecules, Exercise, Overweight.
Full-Text [PDF 327 kb]      
Type of Study: Research | Subject: General
Received: 2016/07/31 | Accepted: 2016/07/31 | Published: 2016/07/31
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Volume 21, Number 3 (Scientific Journal of Kurdistan University of Medical Sciences 2016) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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