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Acne vulgaris:A comparison of therapeutic effects of zinc sulfate v.s tetracycline
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Farokh Rad   1, Roksana Yaghmaie , Siroos Shahsavari |
| 1- , dr_farokh_rad@yahoo.com |
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Abstract: (16334 Views) |
| ABSTRACT
Background and Aim: Acne vulgaris is one of the most common skin problems and affects nearly all adolescents and adults at some time in their lives. Different antibiotics have been used for the treatment of acne vulgaris. In our study the therapeutic effects of zinc versus tetracycline, in the treatment of acne vulgaris was evaluated.
Materials and Methods: In this clinical trial study 82 acne patients, after registration of their characteristics and physical examination, were divided into two groups based on block randomization method. Zinc sulfate with a daily dose of 220 mg (equivalent to 50 mg elemental zinc) and tetracycline hydrochloride with a daily dose of one grams(250 mg every six hours) were prescribed for the intervention and control group respectively, for 12 weeks.
Chi-square and T test were used for the analysis of the results.
Results: There were no significant relationship between the two groups, concerning clinical symptoms and serum zinc level. Also after three months of therapy, the rate of improvement in the two groups was rate of improvement in the two groups statistically was similar.
Conclusion: zinc seems to be as effective as tetracycline in the treatment of acne vulgaris
Key words: Zinc sulfate, Acne vulgaris, Tetracycline |
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| Keywords: Zinc sulfate, Acne vulgaris, Tetracycline |
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Full-Text [PDF 121 kb]
(1760 Downloads)
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Type of Study: Original Research |
Subject:
General
Received: 2009/10/26 | Published: 2006/06/15
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