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Showing 2 results for Seyedzadeh
Dr A Seyedzadeh, Dr D Reissi, Dr N Rezavand,
Volume 10, Issue 4 (scientific journal of kurdistan university of medical sicences 2006)
Abstract
ABSTRACT Background and Aim: after Kidney transplantation. However, in such pregnancies, potential risks of immunosuppressive agents on pregnancy status and fetus should be taken into consideration. There are some reports indicating fetal malformations, preterm labour, abortion and intrauterine growth retardation in such pregnancies. The present study was designed to evaluate the status of pregnancy in women with kidney transplantation in Renal Transplantation Center of the 4 Kermanshah. Women with chronic renal failure can resume normal fertilityth Shahid Mehrab Hospital inMaterials and Methods: records of women who had pregnancy after renal transplantation during 1368-1378 were reviewed. Necessary data concerning the serum creatinine level, blood pressure during pregnancy, age at the time of pregnancy, interval between transplantation and child-birth and occurrence of acute allograft rejection during pregnancy were collected. The newborns were examined twice in a 6 month interval for physical growth, developmental status and major malformations. This was a descriptive-analytic study and the medicalResults: case led to abortion (9%). Immunosuppressive therapy consisted of cyclosporin A and steroid in 3 cases (30%), and cyclosporin A, steroid and azathioprine in 7 cases (70%). The time interval between transplantation and childbirth was 24.6±15.67 months, and the mean age of mothers during pregnancy was 27.22±5.74 years. There was no significant difference between mean systolic and diastolic blood pressures and serum creatinine level before and during pregnancy. There was no acute allograft rejection or any other remarkable problems during pregnancy. Only four newborns, 3 boys and one girl were brought for follow up. 3 cases of pregnancies were unwanted and only one case was intentional. The mean weight of the newborns was 2.62±0.47 Kg, and one of them was underweight (25%). Physical growth and development of these newborns were normal and there was no obvious congenital malformation. 11 pregnancies occurred in 9 women with kidney transplantation, , but oneConclusion: expose mother and fetus to potential risks, this study like other recent studies revealed that supportive measures before pregnancy and close monitoring of the pregnant women by an experienced and multidisciplinary team, may lead to the birth of a healthy baby, without any adverse effect on the function of the allograft Although immunosuppressive agents can cross placental barrier and
Dr Taravat Fakheri, Dr Nazanin Farshchian, Dr Mansour Rezaie, Dr Seyedeh Mozhgan Seyedzadeh,
Volume 20, Issue 6 (Scientifis Journal of Kurdistan University of Medical Sciences 2016)
Abstract
Background and Aim: Ectopic pregnancy is one of the leading causes of death among the women of reproductive age. Injection of single or multiple doses of methotrexate can be used as a therapeutic approach. The aim of this study was to compare the effect of single and multiple-doses of methotrexate therapy on the tubal patency in women with ectopic pregnancy.
Material and Methods: This was an interventional study and included 80 patients with ectopic pregnancy who had been treated with a single dose or multiple doses of methotrexate. After 3 months of hospitalization and treatment, hysterosalpingography was conducted to assess tubal patency. Data were analyzed using SPSS version 21.
Results: The frequencies of ipsilateral tubal obstruction were 12 (30%) and 3 (7.5%) in the patients who had received multiple-doses of methotrexate and single-dose methotrexate respectively. Also, 33 (82.5%) patients in the single-dose methotrexate group and 18 (45%) patients in the multiple-dose methotrexate group did not have bilateral obstruction. There was a significant difference in the frequencies of tubal obstruction between the two groups treated with single and multiple doses of methotrexate (P<0.05).
Conclusion: The incidence of tubal obstruction in women with ectopic pregnancy was significantly lower in single-dose methotrexate group compared to multiple dose methotrexate groups.
Keywords: Ectopic pregnancy, Tubal obstruction, Single-dose methotrexate, Multiple dose methotrexates.
Received: Apr 28, 2015 Accepted: Nov 23, 2015
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