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Showing 2 results for Hosseinkhani
Shabnam Abdi, Dr Mozhdeh Salehnia, Saman Hosseinkhani, Volume 19, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2014)
Abstract
Background and Aim: Vitrification of ovarian tissue is an effective method for preservation of fertility. Many attempts have been made to improve cryopreservation conditions. The aim of this study was to compare the effects of two vitrification methods using two carrier systems straw and cryolock, on the morphology of neonatal mouse ovarian tissue.
Materials and Method: In this experimental study we used NMRI 7-day-old mice. Their ovaries were excised and divided into non-vitrified, vitrified with straw, vitrified with cryolock and toxicity test groups.
In vitrification group, the ovaries were dehydrated in a mixture of 40% ethylene glycol, 30% ficoll 70 and sucrose (EGFS40) for 5 min. Then they were put in a plastic straw or cryolock and were placed into liquid nitrogen and stored for one week. Whereas in the toxicity test group the ovaries were exposed to the cryoprotectant EGFS40 and warming solution procedure without using liquid nitrogen. Then we studied the morphology of ovarian follicles by means of light and electron microscopes.
Result: No significant differences were observed between the groups in regard to the percentages of primordial and primary follicles with normal morphology. But the percentages of normal preantral follicles in the vitrified group using straw were significantly lower than those of other groups. Ultrastructural studies showed signs of degeneration and nuclear shrinkage in follicular cells in some of the preantral follicles in vitrified group using straw.
Conclusion: Vitrification of ovarian tissue using cryolock is more effective for preserveration of the normal morphology of ovarian tissue, compared to vitrification by using straw.
Keywords: Vitrification, Ovarian tissue, Straw, Cryolock.
Received: May 21, 2013 Accepted: May 28, 2014
Kamal Heidari, Mahshid Ahmadian, Ramesh Hosseinkhani, پزشک Zahra Ravankhah, Assistant Professor Ziba Taherian, Zahra Amini, Volume 26, Issue 5 (Scientific Journal of Kurdistan University of Medical Sciences- Special issue 2021)
Abstract
Background and Aim: This study was designed to investigate the results of the non-communicable diseases prevention and control program in Isfahan province under the supervision of the Vice Chancellor for Health of the University of Medical Sciences during the years 2017 to March 2021.
Materials and Methods: In this cross-sectional study, the target group was all the population over 30 years of age in Isfahan province who had referred to health centers for screening programs for non-communicable diseases and risk factors (cardiovascular and diabetes). Breast cancer screening has been performed in women aged 30 to 70 years and colorectal cancer screening has been performed in men and women aged 50 to 70 years.
Results: The number of people diagnosed with diabetes at the end of March 2021 was 148,250 and its prevalence was 11.59%. Also, the number of patients with high blood pressure registered in electronic patient record from 2017 to the end of March 2021 was 249294 (prevalence 19.74%). In colorectal cancer screening, 1593 cases of polyps were detected from 5367 colonoscopy during 4 years of program. Also, by screening 46.9% of the target population, 513 cases of breast cancer were detected.
Conclusion: In the evaluation of the process of diagnosis and patient care, an increase is evident during the years 2017 to 2019, but the decrease in the number of risk assessments and patient care in 2020-2021 is due to the COVID19 pandemic.
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