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Showing 6 results for Heshmati
M Zarei, B Heshmatian, Dr A Sarihi , Dr Mr Rahmani,
Volume 10, Issue 4 (scientific journal of kurdistan university of medical sicences 2006)
Abstract
ABSTRACT Background and Aim: The brain rennin-angiotensin system (RAS) has an important role in the regulation of cardiovascular function. The aim of the present study was to determine the effects of reversible inactivation of the ACe on normotensive and hypertensive rats (renal hypertension). Materials & Methods: Two groups of normotensive Wistar rats were selected for this study. In one group, hypertension was induced by Goldblatt method and another group was subjected to sham procedure. After 6 weeks, tests were performed on anesthetized rats with Urethane (1.5mg/kg). In order to perform bilateral reversible inactivation, lidocaine (1 μ l) was injected through guide cannuli that had been implanted in the ACe. Then direct measurements of femoral blood pressure were recorded just before and 5, 10, 20, 40, and 60 minutes after injection of lidocaine. Considering the baseline values, degree of changes was determined and compared between the two groups. Results: Our results revealed that sham-inactivation led to a significant increase of blood pressure only at 5 minutes after injection (P<0.05). There was no significant difference in blood pressure at different times before and after injection of lidocaine in the hypertensive group. Conclusion: This study concludes that the change in the Ace activity during induction of hypertension is due to the change in RAS activity.
Dr F Heshmati, Dr A Mahoori, Dr H Noorozinia, Dr A Hassani, Dr R Abbacivash,
Volume 12, Issue 4 (Scientific Journal of Kurdistan University of Medical Sciences 2008)
Abstract
ABSTRACT Background and Aim: Strange and unfamiliar setting of the operation room and also fear of operation cause numerous problems for the patient, parents of the patient and anesthesiologist. Prescription of intravenous sedatives or opiates in addition to their side effects leads to more fear and anxiety because of venipuncture. To prevent these problems, we prescribed oral sedatives. Material and Methods : In this controlled double blind clinical trial, sixty children, aged 1-7 year were divided randomly into two groups group 1 received oral Ketamine but placebo was prescribed for group 2. Behavioral changes together with heart rate and respiratory rate alternations were evaluated before and 30 minutes after prescription of the medication. Results: The results of this study showed that the children who received oral ketamin were calmer and separated from their parents easier in comparison to those who received placebo, which showed a significant statistical difference (p<0.001). Also heart and respiratory rates decreased in the patients of ketamine group which revealed a significant difference (p<0.01). Conclusion: It seems that prescription of oral ketamine as a premedication thirty minutes before anesthesia can produce appropriate sedation and a relative decrease in heart and respiratory rates in children, which in turn can lead to less panic, easier separation of children from their parents and facilitation of induction of anesthesia
Dr Rahman Abbasivash, Dr Mir Moosa Aghdashi, Dr Ebrahim Hasani, Dr Farhad Heshmati, Dr Mohammad Shirvani, Dr Ezatollah Rahimi,
Volume 13, Issue 2 (Scientific Journal of Kurdistan University of Medical Sciences 2008)
Abstract
ABSTRACT
Background and Aim: Disadvantages of intravenous regional anesthesia (IVRA) include slow onset, poor muscle relaxation, tourniquet pain, and rapid onset of pain after tourniquet deflation. In this randomized, double-blind study, we evaluated the effect of addition of nitroglycerine (NTG) to lidocaine for improvement of IVRA.
Material and Methods: Forty six patients (20-50 yrs) were randomly assigned into 2 equal groups. Under identical conditions, the control group received 3 mg/kg of lidocaine 0.5% diluted with saline, and the study group received an additional 200 µg NTG. Vital signs and tourniquet pain were measured on the basis of VAS score and recorded before applying tourniquet and 5, 10, 15, 20, and 30 min after administration of anesthetic solution. The onset of sensory and motor block was measured and recorded for all patients. Severity of pain was measured at 5 min, 2, 4, 6, 12, 24, hours after deflation of tourniquet and the total dosage of pethidin injected in the first 24 hours after operation was calculated.
Results: Sensory and motor block began more rapidly in study group than control group (2.61 vs. 5.09 and 4.22 vs. 7.04 min., respectively) (p<0.05). Recovery from sensory and motor block and onset of tourniquet pain were delayed (7.26 vs. 3.43, 9.70 vs. 3.74 and 25 vs. 16.65min., respectively) (p<0.05). Duration of analgesia after tourniquet deflation was more prolonged and tourniquet pain intensity was lower in study group (p<0.05). Fentanyl requirement during operation and meperidine used during first postoperative day and pain intensity at 4, 6, 12 and 24hr postoperatively were lower in study group) p<0.05). No significant side effect was noted in the patients of both groups.
Conclusion: Addition of NTG to lidocaine in intravenous regional anesthesia accelerates the onset of anesthesia and decreases the tourniquet and postoperative pain, without any side effect.
Key words: Intravenous regional anesthesia, Nitroglycerin, Lidocaine
Conflict of Interest: Nill
Received: April 5, 2008 Accepted: July 13, 2008
Dr Rahman Abasivash, Dr Farhad Heshmati, Dr Haydar Noroozinia , Dr Jalal Poorghasem, Dr Samrand Fattah Ghazi,
Volume 15, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2010)
Abstract
ABSTRACT
Background and Aim: Gabapentin (structural analog of GABA), is an antiepileptic drug that its preoperative administration results in postoperative pain reduction. Considering the hypnotic effect of propofol, which is mediated by its attachment to GABAA, this hypothesis was propounded that administration of gabapentin can probably decrease the need for propofol and remifentanil during total intravenous anesthesia.
Materials and Methods: Fifty patients scheduled for elective laparoscopic cholecystectomy, were assigned into two equal groups (n=25) in this randomized double blinded clinical trial. Study group received oral gabapentin (1200mg), and control group received placebo 3hrs before operation. Premedication and induction of anesthesia were the same in all patients. For the maintenance of anesthesia, oxygen and nitrous oxide (50%-50% mixture) and propofol and remifentanil infusion were used. The rate of propofol infusion was adjusted to maintain BIS in the range of 40-60, and dose of remifentanil adjusted to maintain hemodynamic variables in the range of ±20% of baseline values. At the end of anesthesia the duration of anesthesia and the total amount of propofol and remifentanil used for every patient were recorded.
Results: The demographic parameters were similar in both groups (p>0.05). Doses of propofol and remifentanil used for study group were significantly lower than doses used for control group (p<0.01). The mean values of baseline systolic, diastolic, mean arterial, heart rates and BIS in the study group were lower than the corresponding values in the control group (p<0.05).
Conclusion: This study showed that a single dose of gabapentin before operation can decrease the need for propofol and remifentanil in total intravenous anesthesia during laparoscopic cholecystectomy.
Key Words: Gabapentin, Propofol, Remifentanil, Total intravenous anesthesia
Conflict of Interest: Nill
Received: March 8, 2009 Accepted: Sept 23, 2010
Asgar Zerehpoush, Dr Mohammad Bagher Kajbaf, Leila Heshmatifar, Amir Hossein Sadeghi Hosnijeh, Hamed Omidi,
Volume 19, Issue 2 (Scientific Journal of Kurdistan University of Medical Sciences 2014)
Abstract
Background and Aim: Considering the importance of religion orientation in mental health and its stability up to adulthood, we performed this study to investigate religion/Islamic orientation and traits of students' personality on the basis of big five- factors of personality (NEO).
Material and Method: This was a descriptive – analytical study. 272 subjects (men=128, women=144) between 18 and 28 years of age were selected by cluster sampling method and were assessed by means of two questionnaires: 1) Short – form of NEO- Personality Inventory and 2) Islamic-Religious Orientation questionnaire. SPSS software was used for data analysis.
Results: The results of this study showed that all the traits of five factors of personality except for neuroticism had correlation with religious orientation (P<0.01). Factor of openness to experience predicted 0.11 of religion orientation in the students. According to the results of this study, there was a significant difference in religion orientation between males and females (t= -2/21).
Conclusion: In general in our study, the personality traits had correlation with religion orientation and among them openness to experience had a more important role.
Key words: Religion orientation, Five- Factors of Personality NEO, Student.
Received: May 7, 2013 Accepted: Feb 10, 2014
Arezo Heshmati, Omid Saed, Baytamar Jahangir Mohammadi, Saedeh Zenoozian, Fayegh Yousefi,
Volume 23, Issue 5 (Scientific Journal of Kurdistan University of Medical Sciences 2018)
Abstract
Background and Aim: Procrastination, as a pervasive phenomenon in students is interwoven with emotional problems and failure in emotion regulation. The aim of this study was to determine the efficacy of group acceptance and commitment therapy (ACT) on reduction of academic procrastination and improvement of difficulty in emotion regulation in the students of Zanjan University of Medical Sciences.
Material and Method: This was a randomized controlled clinical trial. Statistical population included all of the students of Zanjan University of Medical Sciences in the academic year 2017-2018. After screening, among 500 people, 150 students were selected on the basis of evaluation scales, in the first step. Then, we selected 40 students based on the severity of procrastination and our inclusion and exclusion criteria and divided them into two intervention groups (each group included 10 students) and a control group (n=20) using random number generator 3.1.v software. During the treatment sessions, 7 students were excluded from the two intervention groups. We used Procrastination Assessment Scale for Students (PASS) and Difficulties in Emotion Regulation Scale (DERS) for evaluation of the results. The intervention groups received eight sessions of acceptance and commitment group therapy. Data were analyzed by SPSS software.
Results: The results of repeated measure analysis of variance showed that acceptance and commitment therapy in the intervention group resulted in a significant reduction in: academic procrastination (42.1%), the total score of difficulty in emotion regulation (36.2%), difficulty in engaging in a goal- directed behavior (30.6%), impulse control difficulties (47.5%) and lack of emotional awareness (23.2%)(P<0.05). Also, the results of covariance analysis indicated that with pre-test control, acceptance and commitment therapy, explains 16.1% of the academic procrastination changes and 45.9% of the changes in emotional regulation total score in the intervention group in comparison to the changes in the control group in the long run (P <0.05).
Conclusion: The results of this study have implicit and practical implications for the specialists in order to use long-term acceptance and commitment therapy for reduction of procrastination and emotion regulation difficulties.
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