Dr Hamid Reza Ghasemi Basir, Dr Mohammad Mahdi Majzoobi, Mr Abbas Moradi, Dr Sadi Hesami Novin, Mr Ali Saadatmand,
Volume 28, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2023)
Abstract
Background and Aim: Brucellosis is one of the most common infectious diseases between humans and livestock in Iran. Because of the diagnostic problems of brucellosis, especially in endemic areas, the use of new diagnostic methods is of great importance. Therefore, this study was performed to compare BrucellacapT sensitivity and specificity with the standard Wright tube agglutination test in the diagnosis of Brucella.
Materials and Methods: A total of 100 sera from a patient with suspected symptoms of brucellosis and without laboratory confirmation were studied. Wright, Coombs wright, and BrucellacapT tests were performed at diagnostic threshold titers of 1.160 and 1.80 Sensitivity, specificity, and positive and negative predictive values were evaluated and finally, data were analyzed with SPSS software version 14.
Results: A total of 100 patients were included in the study, of which 45% were female and 55% were male. In titrate 1.160 positive Wright test as a diagnostic threshold, sensitivity, specificity, and positive and negative predictive values for the BrucellacapT test were 97.95, 86.27, 87.27, and 97.97 percent, respectively. In titrate 1.80 positive Wright test as a diagnostic threshold, sensitivity, specificity, and positive and negative predictive values of BrucellacapT test were 98.43, 97.50, 95.45, and 97.05 percent, respectively.
Conclusion: The results showed that the BrucellacapT test in the studied cut points has acceptable sensitivity, specificity, and positive and negative predictive value for the diagnosis of brucellosis and the diagnostic and accuracy of this test in the titrate 1.160 is very close to the Coombs Wright test.
