:: Volume 26, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2021) ::
SJKU 2021, 26(1): 22-32 Back to browse issues page
Thoracic CT Scan Findings in Patients with HIV/TB co-infection before and after treatment
Payam Mehrian1 , Payam Tabarsi1 , Maasumeh Nouruzi2, Fatemeh Kheiridoost2, Zahra Ghomi 3
1- Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Telemedicine Research center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
3- Shohade-E-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , zgh1881@gmail.com
Abstract:   (680 Views)
Background and Aim: Pulmonary tuberculosis (TB) infection is common in patients infected with the Human immunodeficiency virus (HIV). In this study, we evaluated thoracic CT scan findings of HIV/TB co-infection, before and after anti-TB treatment.
Materials and Methods: In this retrospective cross-sectional study, pre-and post-treatment thoracic CT scans of patients diagnosed with HIV and definite pulmonary TB infection were evaluated.
Results: A total of 101 patients (64 male, 37 female, mean age of 43±3.4) were included. The most common findings before treatment of TB were mediastinal or hilar lymphadenopathy with hypodense center (41.58%) and free pleural effusion (32.67%). The prevalence of these findings decreased to half after anti-TB treatment (P= 0.009 and P= 0.003 respectively). Loculated pleural effusion showed increased prevalence after treatment (P= 0.031) with no significant change in the prevalence of bronchiectasis, solitary pulmonary nodule, and lymphadenopathy without a hypodense center.
Conclusion: The most prevalent thoracic CT scan findings in patients with HIV/TB co-infection before anti-TB treatment were lymphadenopathy with the hypodense center, pleural effusion, and ground-glass opacities. After treatment, numerous changes in imaging manifestations might be seen. The remaining residual CT scan findings (including bronchiectasis, lymphadenopathy with a hypodense center, and solitary pulmonary nodule) require more attention for accurate interpretation of thoracic CT scans in HIV patients.
Keywords: Tuberculosis, Pulmonary, HIV, Multidetector Computed Tomography
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Type of Study: Original Research | Subject: General
Received: 2019/09/30 | Accepted: 2020/08/19 | Published: 2021/03/30


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Volume 26, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2021) Back to browse issues page