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Evaluation of the analgesic and anti-inflammatory effects of aqueous extract of peppermint (Mentha piperita)
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Arash Abdolmaleki1   , Ali Rajabi2 , Fariborz Sanginabadi3 |
1- Hamedan Branch, Islamic Azad University, , Abdolmalekiarash1364@gmail.com
2- Ardebil University of Science
3- Social Security Organization, Ghorveh, |
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Abstract: (17874 Views) |
| Background and Aim: The aim of this study was to investigate the analgesic and anti-inflammatory effects of aqueous extract of mint plant which has been used in folk medicine as a pain reliever.
Materials and Methods: In this experimental study, male NMRI mice received intra-peritoneal injections of peppermint extract with different doses of 20,40,60,90 and 120mg/kg. Then anti-inflammatory and analgesic effects of peppermint were determined by using formaldehyde and xylene tests. Anova and Tukey test were used for data analysis.
Results: All doses of peppermint extract showed significant anti-inflammatory effect on the ear inflammation induced by xylene in comparison to the control group (p<0.05). Doses of 40, 60, 90, 120 mg/ kg significantly reduced the pain (p<0.05), but the group treated with the dose of 20mg/kg showed no significant reduction of the pain.
Conclusion: The results of this study are indicative of anti-inflammatory and analgesic effects of peppermint. We recommend further studies on this subject in the future. |
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| Keywords: Mentha piperita, Anti-inflammatory, Analgesic, Mice NMRI |
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Full-Text [PDF 708 kb]
(6149 Downloads)
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Type of Study: Original Research |
Subject:
General
Received: 2013/04/27 | Published: 2013/05/15
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