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Showing 3 results for Irritable Bowel Syndrome
Dr Mohsen Parviz, Dr Shahriar Gharibzadeh, Shohreh Ebadian, Mohammad Hosein Taheri,
Volume 11, Issue 4 (3-2007)
Abstract
Background and Aim: Since enteric nervous system is a complicated network and calls for more investigations, we decided to develop a model for myoelectric activity of small intestine by use of artificial nerve networks, in order to reach a better understanding of I.B.S. According to empirical knowledge concerning I.B.S, serotonin level in enteric nervous system increases and this system becomes more excitable and active. The aim of this study was to prove these issues by use of mathematical models.
Materials and Methods: MTLAB 6.5 soft ware was used in this project. Artificial nerve networks, equivalent to enteric nervous system were designed.
Results: By making use of artificial nerve networks, amplitude, time and number of spikes in the myoelectric curve of small intestine were determined which were compatible with empirical information.
Conclusion: Using artificial nerve networks, the effect of increased level of serotonin as a pathophysiological factor, on bowel movement in IBS was established. This study can pave the way for designing other artificial networks to assess potential effects of drugs or developing more effective methods for treatment of I.B.S.
Rahmatollah Iri, Dr Farshad Sheikhesmaeili, Nima Fattahi, Romina Reshadat, Behzad Saeedi, Zahra Shahabbaspoor, Lida Emami, Dr Pedram Ataee, Dr Ghobad Moradi, Dr Karim Sharifi,
Volume 22, Issue 1 (4-2017)
Abstract
Background and Aim: Irritable bowel syndrome is a common gastrointestinal disease which is characterized by abdominal pain and altered bowel habits. This study aimed to investigate the prevalence of irritable bowel syndrome and its related factors in the general population in Sanandaj in 2013-2014.
Materials and Methods: This cross-sectional study was conducted in Sanandaj for a period of 12 months, from the summer of 2013 to the summer of 2014. Considering the design effect, a population sample of 430 were selected via random cluster sampling method. ROME III criteria were used for diagnosis of IBS. Logistic regression was used to accomplish the qualitative objectives and multivariate analysis for categorical variables. We used STATA11 software for statistical analysis.
Results: We found a prevalence rate of 10.63% for irritable bowel syndrome in the general population in Sanandaj. Concerning gender distribution, the prevalence rates were 11.5% and 9.96% for males and females respectively, which had no statistically significant difference (OR=1.184, 95% CI=0.574 – 2.439). Although the disease was more prevalent in the patients between 30-40 years of age compared to other age groups, this difference was not statistically significant (OR=0.679, 0.95 CI=0.189, 2.441).
Conclusion: The results of this study showed that the prevalence rate of IBS was higher in Sanandaj city in comparison to other parts of Iran, which can be related to several factors such as diet and lifestyle. Because of the high prevalence of IBS in Sanandaj, we recommend further studies for identification of the causes of this disorder and its exacerbating factors in this city.
Keywords: Irritable bowel syndrome, Prevalence rate, Population-based study, Iran.
Received: Jul 24, 2016 Accepted: Nov 7, 2016
Habibollah Khaledian, Baran Parhizkar, Farshad Shikhesmaeili, Masoud Moradi,
Volume 24, Issue 3 (7-2019)
Abstract
Background and Aim: The aim of this study was to compare personality characteristics and coping strategies between the patients with irritable bowel syndrome and normal individuals.
Material and Method: In this cross sectional study we selected 200 people (100 irritable bowel syndrome patients and 100 normal individuals) on the basis of convenient method. We used two questionnaires including the NEO- Five Factor personality Inventory and Lazarus- Folkman coping Questionnaire for data collection. Data were analyzed by t-test and Mann- whitney U Test.
Results: The results showed that the mean scores of neuroticism factor in the patients with irritable bowel syndrome were higher than those in the normal individuals. While the mean scores of extraversion and conscientiousness factor in the normal subjects was higher than those in the patients with irritable bowel syndrome. There were no significant differences between the two groups in openness and agreeableness. Data showed that normal individuals compared to the patients with irritable bowel syndrome, used more problem- oriented coping styles. There were no significant differences between the two groups in regard to the escape-avoidance variable.
Conclusion: The results showed that IBS was affected by personality characteristics and coping strategies. Study of these factors can have many applications in the fields of research, etiology and treatment of this disease.
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