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Showing 3 results for Hossieni
Dr Seyed Mohammad Hossieni Kasnavieh, Dr Mojtaba Chahardoli , Dr Hamed Basir Ghafouri, Dr Alireza Sedghi, Dr Tayeb Ramim,
Volume 19, Issue 4 (Scientific Journal of Kurdistan University of Medical Sciences 2014)
Abstract
Background and Aim: Severe arterial injuries in the hand can be hazardous to the limbs and even life- threatening. The aim of this study was to investigate the management methods in the patients with acute injuries of the ulnar or radial artery in the emergency department.
Material and Methods: This cross-sectional prospective study was conducted in the emergency department of Sina Hospital in Tehran, from 2012 to 2013. Stable vital signs, wrist and forearm laceration with jumper or active bleeding, radial or ulnar artery injury one or both were among our inclusion criteria. Vital signs, level of consciousness, coincident injuries were assessed and physical examination was performed in all patients. We recorded time of patient arrival, primary and secondary treatment, and consultation and follow up visits in emergency department or ward.
Results: 50 patients (3 females and 47 males) with a mean age of 30.34y ± 9.69y were enrolled. The first step was to examine and pack up bleeding. The most common injury was due to sharp instruments (84%) and the most common injured artery was radial artery (68%).The mean duration of the first treatment was 1.24 ± 0.93 min. 37 patients (74%) were treated by ligation in the emergency room and the remaining 13 patients (26%) were sent to the operating room for repair and vascular anastomosis by our vascular surgeon. Mean values of duration for ligation were 16.72 ± 13.83 min and 117.76 ± 114 min in emergency medicine and vascular surgery groups, respectively that showed a significant difference between the two groups (p= 0.0001). The overall duration of hospitalization for the patients was 69.04 ± 82.74 hour (5- 311 hours).
Conclusions: We can conclude that the radial or ulnar artery ligation considering its indications or contraindications, in emergency room can play an important role in the recovery of patient's hemodynamic status and speed up of the next step of patient’s treatment.
Key words: Radial artery, Ulnar artery, Ligation, Repair, Hospital stay
Received: Dec 28, 2013 Accepted: Jul 23, 2014
Behnam Amirpour-Najafabadi, Mahsa Gholami, Parvin Zarie, Sirvan Hossieni, Mehdi Sadegh,
Volume 23, Issue 5 (Scientific Journal of Kurdistan University of Medical Sciences 2018)
Abstract
Background and Aim: Peripheral and central nervous system neuropathy occur in chronic diabetes with uncontrolled hyperglycemia. Beneficial effects of sodium valproate have been demonstrated in neurodegenerative diseases. Sodium valproate has neuroprotective and regenerative effects via modifications in gene expression. In this study, we investigated effects of sodium valproate on the modifications in the hippocampal levels of NF-KB, AP-1, S100B and GFAP as a consequence of alloxan induced diabetes.
Material and Methods: This experimental study included 24 adult male C57B15/J mice. Diabetes was induced by injection of alloxan (150 mg/kg; i.p.). Sodium valproate was administrated (100 mg/kg; i.p) every 72 hours for two months. Fasting blood sugar levels were measured at the beginning and at the end of the experiment. Then animals were killed, their hippocampuses were extracted and prepared for measurement of biochemical factors by ELISA kits.
Results: Increased blood glucose levels due to alloxan induced diabetes were significantly reduced following sodium valproate administration (P<0.05). Also, chronic sodium valproate administration in diabetic animals significantly reduced elevated levels of hippocampal NF- KB, S100B and GFAP (P<0.05). Conclusion: It seems that sodium valproate can adjust diabetes induced modifications in the biochemical factors of the hippocampus which are indicators of cell damage, and maybe effective in prevention of diabetic neuropathy
Sahar Hossieni, Shahram Sadeghi, Mohammad Hossein Saghi, Seyed Kamal Ghadiri,
Volume 24, Issue 4 ( Scientific Journal of Kurdistan University of Medical Sciences 2019)
Abstract
Background and Aim: Endocrine Disrupting Chemicals (EDCs), and potential EDCs are mostly man-made, found in various materials such as pesticides, metals, additives or contaminants in food, and personal care products. Phthalates are a group of these compounds that are carcinogenic to animals and can cause fetal death and congenital anomalies. The aim of this study was to investigate the photocatalytic process using GO/ZnO nanocomposites under LED irradiation for removal of Endocrine Disrupting Chemicals (EDCs) from aqueous solutions.
Materials and Methods: In this study, GO/ZnO nanorods were characterized by, Field emission scanning electron microscopy, transmission electron microscope, and Brunauer–Emmett–Teller surface area analysis. A Central Composite Design was used to optimize the reaction parameters for the removal of DEP by GO/ZnO. The four main reaction parameters optimized in this study were the following: the LED radiation time, pH, and the initial concentration of phthalates and the concentration of ZnO and graphene-oxide. The interaction between the four parameters was studied and modeled using the Design Expert 10 software. Phthalate detected by HPLC apparatus equipped with a UV detector at 225 nm wavelength with methanol (90%) and Acetonitrile (10%) phases.
Results: The results of FE-SEM and TEM showed that the ZnO is composed of a bar and separate face. Based on the peak obtained, the diameter and length of the nanorods are 20-60 and 200 nm respectively. A maximum reduction of 90% of DEP was achieved at pH 5 and 120 minutes. The results represent the prediction of a model fitted from the Quadratic model (p-value<00001).
Conclusion: The interaction of variables showed that the maximum effect was belonged to the pH and the time in the process reactions. Also, the results showed that the GO/ZnO low power LED irradiation can be used as an effective method for the removal of EDCs from environmental.
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