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Showing 2 results for Aghamiri
Dr Sakineh Mohammad-Alizadeh-Charandabi, Dr Mozhgan Mirghafourvand , Vida Aghamiri , Dr Hossein Nazemiyeh, Sedigheh Soltanpoor,
Volume 19, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2014)
Abstract
Background and Aim: Nowadays, because of the concern about risks of hormone-therapy, many physicians and women prefer phyto-estrogens for the treatment of menopausal symptoms. Hop is a plant with potent phyto-estrogenic ingredients. However, its effect on the symptoms has been evaluated only in one clinical trial. The purpose of this study was to evaluate the efficacy of hop (Humuluslupulus L.) in the treatment of early menopausal symptoms and hot flashes (primary outcomes).
Material and Method: In this randomized, double-blind, placebo controlled trial, 60 perimenopausal women were randomly assigned to two equal groups (n=30). One group received hop tablets, 500 mg/day and other group received placebo tablets 500 mg/day, for 90 days. Early menopausal symptoms were assessed by means of Greene Scale (0-63) before and at the 4th, 8th and 12th weeks after intervention. ANOVA was used for data analysis.
Result: There was no loss to follow-up during the 12 weeks of intervention. The mean Greene total score was significantly lower in the hop group in comparison to the placebo group at the 4th (adjusted difference: -8.3, 95% confidence interval: -9.7 to -6.9),8th (-14.6, -16.5 to -12.7) and12th (-18.2, -20.5 to -16.0) weeks after intervention. No side effects were reported in this study.
Conclusion: Hop effectively reduced the early menopausal symptoms and the number of hot flushes in perimenopausal women. Therefore, phytoestrogens can be used for the treatment of climacteric symptoms in the perimenopausal women.
Keyword: Early menopausal symptoms, Hop (Humuluslupulus L.), Perimenopause, Randomized clinical trials
Nematollah Heidarloo, Hamid Reza Baghani, Prof. Seyed Mahmoud Reza Aghamiri,
Volume 26, Issue 4 (Scientific Journal of Kurdistan University of Medical Sciences 2021)
Abstract
Background and Aim: Beam shaper applicator is one of the dedicated applicators for intraoperative electron radiotherapy which is usually employed for large tumors irradiation. Due to the high weight and lack of possibility of direct placement on the patient’s body, a considerable air gap exists between the applicator and patient. Therefore, determination of the effective position of electron source (SSDeff) is absolutely necessary to correct the applicator output for air gap effect and accurate delivery of the prescribed dose to the patient. The aim of this study was to determine the SSDeff for all square fields of beam shaper applicator at different electron energies using Monte Carlo (MC) simulation.
Materials and Methods: At first, the head of LIAC accelerator and beam shaper applicator were simulated by MCNPX MC code and then, the validity of the simulated model was evaluated through comparing the calculated percentage depth dose (PDD) curves at different field sizes and energies with the corresponding practiacal values. After verifying the simulated model, the SSDeff was determined for different field sizes and electron energies using inverse square law (ISL) method.
Results: The results showed that the SSDeff is a function of electron energy and radiation field size. Dependency of SSDeff on field size variations was much more than that on the alterations in the electron energy. Generally, increase in the field size or electron energy led to increase in SSDeff.
Conclusion: The determined SSDeff values for the electron beam of the beam shaper applicator in our study, can be used to correct the electron beam output for clinical purposes.
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| مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences |
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