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:: Volume 12, Issue 4 (Scientific Journal of Kurdistan University of Medical Sciences 2008) ::
SJKU 2008, 12(4): 63-68 Back to browse issues page
Evaluation of the effect of ketamine as oral premedication on quality of pediatric anesthesia
F Heshmati Dr , A Mahoori Dr, H Noorozinia Dr, A Hassani Dr, R Abbacivash Dr
Abstract:  

  ABSTRACT

  Background and Aim: Strange and unfamiliar setting of the operation room and also fear of operation cause numerous problems for the patient, parents of the patient and anesthesiologist. Prescription of intravenous sedatives or opiates in addition to their side effects leads to more fear and anxiety because of venipuncture. To prevent these problems, we prescribed oral sedatives.

  Material and Methods : In this controlled double blind clinical trial, sixty children, aged 1-7 year were divided randomly into two groups group 1 received oral Ketamine but placebo was prescribed for group 2. Behavioral changes together with heart rate and respiratory rate alternations were evaluated before and 30 minutes after prescription of the medication.

  Results: The results of this study showed that the children who received oral ketamin were calmer and separated from their parents easier in comparison to those who received placebo, which showed a significant statistical difference (p<0.001). Also heart and respiratory rates decreased in the patients of ketamine group which revealed a significant difference (p<0.01).

Conclusion: It seems that prescription of oral ketamine as a premedication thirty minutes before anesthesia can produce appropriate sedation and a relative decrease in heart and respiratory rates in children, which in turn can lead to less panic, easier separation of children from their parents and facilitation of induction of anesthesia
Keywords: Key Words: Oral premedication, Ketamine, Pediatric anesthesia
Full-Text [PDF 107 kb]      
Type of Study: Research | Subject: General
Received: 2009/04/14
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Volume 12, Issue 4 (Scientific Journal of Kurdistan University of Medical Sciences 2008) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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