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Transdermal fentanyl versus intra venous morphine in postthoracotomy pain management
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Alireza Bameshki1   , Mehryar Taghavi Gilani , Ghasem Soltani , Nahid Zirak |
| 1- , bameshkiar@mums.ac.ir |
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Abstract: (13212 Views) |
| ABSTRACT
Background and Aim: Transdermal fentanyl can be used for treatment of chronic pain and postoperative pain. The aim of this study was to compare the effect of transdermal fentanyl with that of IV morphine on post thoracotomy pain and their complications.
Material and Methods: 40 patients ASA I, II who had been selected randomly for thoracotomy, was divided into two similar groups. After operation, morphine 0.1mg/kg was administered IV Q6h for morphine group in ICU and in fentanyl group fentanyl patch 50 μg/h was administered 2 hours before operation. Also in both groups morphine 0.1mg/kg was infused PRN. SPSS13 was used for data analysis & P<0.05 was considered significant.
Results: Demographic parameters such as age, sex, weight and smoking were similar in two groups. Decrease of blood pressure was more in morphine group but it was not significant & increase of heart rate was more common in fentanyl group (p<0.01). Pain relief was more in fentanyl group (3.2 vs 4.6 score based on VAS). Morphine consumption in M group was three times more than that of fentanyl group (71±3.16 vs 22.5±9.79).
Conclusion: Transdermal fentanyl was more effective than IV morphine for controlling post thoracotomy pain and respiratory changes were similar in both groups. Hypotension in morphine group was more common than that of fentanyl group but tachycardia was more prevalent in fentanyl group.
Key word: Thoracotomy, Postoperative pain, Transdermal fentanyl, intravenous morphine
Conflict of Interest: Nill
Received: Dec 21, 2009 Accepted: March 13, 2010 |
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| Keywords: Thoracotomy, Postoperative pain, Transdermal fentanyl, intravenous morphine |
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Full-Text [PDF 755 kb]
(2481 Downloads)
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Type of Study: Original Research |
Subject:
General
Received: 2010/06/3 | Accepted: 2016/03/11 | Published: 2016/03/11
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