:: Volume 20, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2015) ::
SJKU 2015, 20(3): 86-93 Back to browse issues page
Investigatation of diagnostic value of random urine protein/creatinine ratio in pre-eclampsia
Farnaz Zandvakili Dr, Sara Matini Dr, Ezatollah Rahimi Dr 1, Shoaleh Shahgheibi Dr, Ebrahim Ghaderi Dr, Naser Reshadmanesh
1- , e_rahimi258@hotmail.com
Abstract:   (4504 Views)
Background and Aim: Standard diagnostic procedure for significant proteinuria is based on 24-hour urine collection. However, this method is time consuming and may lead to incomplete urine collection. Instead, random urine protein/creatinine ratio could be used as an alternative method for evaluation of proteinuria. This study investigates the diagnostic value of random urine protein/creatinine ratio for the diagnosis of pre-eclampsia. Material and Methods: In this cross-sectional study a group of 96 patients with pre-eclampsia and a group of healthy pregnant women were recruited. All cases were checked for urine protein by assessing urine analysis, 24-hour urine, and random urine protein/creatinine ratio. Data were analyzed using SPSS and ROC curve. Then a cutoff point of random urine protein/ creatinine ratio was determined. Results: Area under the curve for random Pr/Cr was calculated as 0.785 (CI %95: 0.721-0.849) (p<0.001). The best diagnostic cutoff point for protein/creatinine ratio was determined as 0.325. In this point sensitivity and specificity were 81.3% and 66.7% respectively. As a result, a positive correlation between random urine protein/creatinine ratio and systolic blood pressure (r = 0.284, p = 0.005) was observed. Conclusion: Based on these results, random urine protein/creatinine ratio in a cutoff point of 0.325 could be suggested for preeclampsia. Keywords: Preeclampsia, Proteinuria, Diagnosis. Received: Oct 19, 2014 Accepted: Feb 24, 2015
Keywords: Preeclampsia, Proteinuria, Diagnosis.
Full-Text [PDF 336 kb]   (7852 Downloads)    
Type of Study: Research | Subject: General
Received: 2015/07/12 | Accepted: 2015/07/12 | Published: 2015/07/12



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Volume 20, Issue 3 (Scientific Journal of Kurdistan University of Medical Sciences 2015) Back to browse issues page