[Home ] [Archive]   [ فارسی ]  
:: Volume 20, Issue 2 (Scientific Journal of Kurdistan University of Medical Sciences 2015) ::
SJKU 2015, 20(2): 24-31 Back to browse issues page
Correlation of androgenetic alopecia and early onset coronary heart disease in men
Hashem Kazerani Dr 1, Ali Ebrahimi Dr2, Behzad Hajimoradi Dr2, Laleh Iaghoubpour Dr3
1- Associate Professor Kermanshah University of Medical Sciences , dr-hashemkazerani@Kums.ac.ir
2- Assistant Professor Kermanshah University of Medical Sciences
3- Kermanshah University of Medical Sciences
Abstract:   (1982 Views)
Background and Aim: Coronary heart disease (CHD) is the main cause of death in all countries. In addition to the known risk factors, other causes may be related to this disease. The association of CHD with androgenetic alopecia (AGA) has been a subject of discussion which can be explained on the grounds that testosterone level increases in androgenetic alopecia. The aim of this study was to assess this correlation in the men less than 50 years of age. Material and Methods: This case-control study included 250 men less than 50 years of age, who had referred to Imam Ali Hospital in Kermanshah for evaluation of chest pain and exercise test (EST). The participants were divided into two groups: 120 men with positive EST in the case group and 130 men with negative EST in the control group. The history, clinical, and paraclinical information were obtained and recorded in questionnaires. Pattern of alopecia was assessed based on Hamilton baldness scale by a dermatologist. Using SPSS version 16, data were analyzed by Mann–Whitney U test, and Kruskal–Wallis test. Results: Findings of this study revealed a significant relationship between AGA and early onset of IHD in men (P=0.04). Men with AGA (especially vertex alopecia) had positive EST 1.5 times more than those with normal hair pattern. Also, AGA showed a significant correlation with high blood pressure, total cholesterol, LDL level, and higher level of free testosterone. Conclusion: Increased level of testosterone in AGA can accelerate atherosclerosis in men with early AGA, especially vertex pattern, which may result in IHD. This process can advance rapidly in the presence of systolic hypertension and hypercholesterolemia. Therefore, we recommend evaluation of coronary heart disease and control of its risk factors in adult men with early onset AGA. Keywords: Coronary artery disease, Androgenetic alopecia, Exercise test Received: July 25, 2014 Accepted: Jan 12, 2015
Keywords: Coronary artery disease, Androgenetic alopecia, Exercise test
Full-Text [PDF 1027 kb]   (529 Downloads)    
Type of Study: Research | Subject: General
Received: 2015/04/27 | Accepted: 2015/04/27 | Published: 2015/04/27
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code



XML   Persian Abstract   Print



Volume 20, Issue 2 (Scientific Journal of Kurdistan University of Medical Sciences 2015) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 3731