[Home ] [Archive]   [ فارسی ]  
:: Volume 11, Issue 2 (Scientific Journal of Kurdistan University of Medical Sciences 2006) ::
SJKU 2006, 11(2): 35-42 Back to browse issues page
Evaluation of the effect of anti-biotherapy following surgery of acute supurative appendicitis, on some infection indicators
Shahnam Askarpoor Dr 1, Mohammad Hosein Sarmast Shooshtari Dr2
1- Assistant Professor , Shahnam_Askarpour@yahoo.com
2- Associate Professor
Abstract:  
Background and Aim: Prophylactic anti-biotherapy in acute appendicitis is necessary to prevent peritonitis and gangrene of appendix. But anti-biotherapy in the first 24 hours after appendectomy in acute supurative cases requires further investigations. The aim of this study was to evaluate the effect of anti-biotherapy on prevention of the complications of the surgery and duration of hospitalization. Materials and Methods: This is a prospective blind clinical trial study from 1379 to 1382 in 3 university`s hospitals in AHWAZ including all the cases of supurative appendicitis. In this study 200 patients were divided into two equal groups. In one group cefazolin and metronidazole were prescribed for the purpose of prophylaxis before surgery and in the other group, in addition to prophylactic anti-biotherapy, cefazolin and metronidazol continued for another 24h after surgery. Then the patients were followed up for 2 months to be examined for wound infection, abdominal and pelvic abscesses, wound dehiscence and duration of hospitalization. Results: In this study, 200 patients 56% male and 44% female were divided into two equal groups. Mean age of the patients was 18.5 years (15-40). The first group received antibiotics for 24h after operation. But wound infection and post operative fever were detected in 4% and 6% of these patients respectively and mean days of hospitalization was 2.6 days (2-7 days). In the second group without post operative anti-biotherapy incidence rate of wound infection and post operative fever were 4% and 8% respectively and the mean days of hospitalization was 2.8 days (2-7 days). There were no abdominal or pelvic abscess and wound dehiscence in both groups. In this study incidence of wound infection (p=1.00) and post operative fever (p=0.58) and mean days of hospitalization (p=0.68) were similar in both groups and there were no significant statistical differences. Conclusion: It seems that post operative anti-biotherapy in supurative appendicitis is of no value in reducing the incidence of wound infection, post operative fever and mean number of days of hospitalization.
Keywords: Acute appendicitis, Complication, Wound infection, Fever, Hospitalization
Full-Text [PDF 148 kb]      
Type of Study: Research | Subject: General
Received: 2009/05/13
Send email to the article author

Add your comments about this article
Your username or Email:

Write the security code in the box >


XML   Persian Abstract   Print



Volume 11, Issue 2 (Scientific Journal of Kurdistan University of Medical Sciences 2006) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
Persian site map - English site map - Created in 0.06 seconds with 30 queries by YEKTAWEB 3647