[Home ] [Archive]   [ فارسی ]  
:: Volume 18, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2013) ::
SJKU 2013, 18(1): 67-74 Back to browse issues page
Evaluation of the analgesic and anti-inflammatory effects of aqueous extract of peppermint (Mentha piperita)
Arash Abdolmaleki * 1, Ali Rajabi 2, Fariborz Sanginabadi Dr3
1- Hamedan Branch, Islamic Azad University, , Abdolmalekiarash1364@gmail.com
2- Ardebil University of Science
3- Social Security Organization, Ghorveh,
Abstract:   (13293 Views)
Background and Aim: The aim of this study was to investigate the analgesic and anti-inflammatory effects of aqueous extract of mint plant which has been used in folk medicine as a pain reliever. Materials and Methods: In this experimental study, male NMRI mice received intra-peritoneal injections of peppermint extract with different doses of 20,40,60,90 and 120mg/kg. Then anti-inflammatory and analgesic effects of peppermint were determined by using formaldehyde and xylene tests. Anova and Tukey test were used for data analysis. Results: All doses of peppermint extract showed significant anti-inflammatory effect on the ear inflammation induced by xylene in comparison to the control group (p<0.05). Doses of 40, 60, 90, 120 mg/ kg significantly reduced the pain (p<0.05), but the group treated with the dose of 20mg/kg showed no significant reduction of the pain. Conclusion: The results of this study are indicative of anti-inflammatory and analgesic effects of peppermint. We recommend further studies on this subject in the future.
Keywords: Mentha piperita, Anti-inflammatory, Analgesic, Mice NMRI
Full-Text [PDF 708 kb]   (2234 Downloads)    
Type of Study: Research | Subject: General
Received: 2013/04/27
Send email to the article author

Add your comments about this article
Your username or Email:

Write the security code in the box >


XML   Persian Abstract   Print



Volume 18, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2013) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 3705