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:: Volume 25, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2020) ::
SJKU 2020, 25(1): 93-104 Back to browse issues page
Comparing the Effects of Orthodentol and Chlorhexidine Mouthwash on Prevention of Ventilator-Associated Pneumonia in Patients of Intensive Care Unit: A Randomized Controlled Clinical Trial
Rasool Kawyannejad1 , Javad AminiSaman2 , Saeed Mohammadi2 , Shila Amini3 , Maryam Mirzaei4 , HasanAli Karimpour 5
1- Instructor, Department of Anesthesia, School of Allied Medical Sciences, Kermanshah University of Medical Sciences, Kermanshah, Iran
2- Department of Anesthesia, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
3- Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
4- Department of Anesthesia, School of Allied Medical Sciences, Kermanshah University of Medical Sciences, Kermanshah, Iran
5- Department of Anesthesia, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran , hooman.karimpour@yahoo.com
Abstract:   (448 Views)
Background and Aim: Ventilator-associated pneumonia is a common, serious and costly complication in patients of intensive care units. Oral hygiene is one of the important clinical measures to reduce the amount of pulmonary infection in these patients. Therefore, this study compares the effects of chlorhexidine and orthodontal mouthwashes on prevention of pulmonary infection in patients with endotracheal tracheal intubation under mechanical ventilation in intensive care units.
Materials and Methods: This double-blind clinical trial study was performed on 60 patients undergoing mechanical ventilation in two groups of intervention (n = 30) and control (n = 30) in ICU department of Imam Reza hospital in Kermanshah. In the control group, chlorhexidine (0.2%) mouthwash and in the intervention group, Ortodontol mouthwash was used three times a day. Data on the rate of early and late pneumonia were compared based on CPIS criteria applying t-test and Chi-square.
Results: The incidence of early and delay pneumonia in the intervention group was lower than that of control, but no significant difference was observed (P >0.05). The overall frequency of pulmonary infection in the intervention group was significantly lower than the control group (P = 0.03). The frequency of pneumonia causes was lower in the intervention group, but this decrease was statistically significant in Staphylococcus aureus (P = 0.03).
Conclusion: According to the results of this study, orthodontol mouthwash can be effective in reducing the incidence of pulmonary infection associated with mechanical ventilation.
Keywords: Oral Hygiene, Pneumonia, Intensive Care Unit, Endotracheal Tube
Full-Text [PDF 621 kb]   (138 Downloads)    
Type of Study: Research | Subject: General
Received: 2019/04/27 | Accepted: 2019/10/20 | Published: 2020/03/29
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Kawyannejad R, AminiSaman J, Mohammadi S, Amini S, Mirzaei M, Karimpour H. Comparing the Effects of Orthodentol and Chlorhexidine Mouthwash on Prevention of Ventilator-Associated Pneumonia in Patients of Intensive Care Unit: A Randomized Controlled Clinical Trial. SJKU. 2020; 25 (1) :93-104
URL: http://sjku.muk.ac.ir/article-1-4951-en.html


Volume 25, Issue 1 (Scientific Journal of Kurdistan University of Medical Sciences 2020) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
مجله علمی دانشگاه علوم پزشکی کردستان Scientific Journal of Kurdistan University of Medical Sciences
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