fa ارتباط امنیت غذایی با الگوی آتروژنیک قند و پروفایل چربی خون در زنان بزرگسال: یک مطالعه‌ی مقطعی مبتنی بر جمعیت در زابل، جنوب شرق ایران علوم تغذیه و رژیم درمانی Nutrition Sciences and Diet Therapy پژوهشي اصیل Original Research <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">زمینه و هدف:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">اختلالات قند و چربی خون از جمله عوامل خطرساز بیماری&shy; های قلبی عروقی می&shy;باشند که با وضعیت تغذیه در ارتباط می&shy;باشند. این مطالعه با هدف تعیین ارتباط وضعیت امنیت غذایی با الگوی آتروژنیک قند و چربی خون در زنان انجام شد.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">مواد و روش&shy; ها:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">در این مطالعه مقطعی، 630 زن 50-18 سال به‌طور تصادفی خوشه&shy; ای انتخاب شدند. وضعیت امنیت غذایی با استفاده از پرسش&shy;نامه &shy;ی مقیاس ناامنی غذایی خانوار </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">(HFIAS)</span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">ارزیابی شد که روایی و پایایی آن برای جمعیت ایرانی تأیید شده است. غلظت سرمی گلوکز </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">)</span><span dir="LTR" new="" roman="" style="font-family:" times="">(FBS</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">،</span></span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> تری&shy;گلیسرید </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">(TG)</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">، کلسترول تام </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">(TC)</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">، لیپوپروتئین با چگالی پایین </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">(LDL)</span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">و لیپوپروتئین با چگالی بالا </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">(HDL)</span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">اندازه&shy; گیری و نسبت&shy; های </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">LDL/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">TC/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> و </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">TG/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> در مورد هر&shy;یک از شرکت &shy;کنندگان محاسبه شد.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">یافته&shy; ها:</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> میانگین غلظت سرمی </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">TG</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> و نسبت </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">TG/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> در زنان دارای ناامنی غذایی متوسط و شدید به‌طور معنی&shy; داری بیشتر از زنان دارای امنیت غذایی بود (0/002=</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">P</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">). پس از تعدیل عوامل مداخله&shy; گر، شانس داشتن هیپرتری&shy;گلیسریدمی (0/018= </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">P</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">، 1/63=</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">OR</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">) و نسبت </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">TG/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> بالا (0/030=</span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">P</span></span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">، 1/52=</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">OR</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">)، زنان دارای ناامنی غذایی متوسط و شدید به‌طور معنی&shy; داری بیشتر از زنان دارای امنیت غذایی بود. با این حال، ارتباط معنی &shy;داری بین وضعیت امنیت غذایی افراد و شانس داشتن گلوکز خون مختل، هیپرکلسترولمی، </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">LDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> بالا، </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> پایین و نسبت&shy; های غیرطبیعی </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">LDL/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> و </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">TC/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> یافت نشد.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">نتیجه&shy; گیری:</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> ناامنی غذایی با شانس بالاتر ابتلا به هیپرتری&shy;گلیسریدمی و نسبت </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">TG/HDL</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> بالا در زنان ارتباط داشت.</span></span></span></span></span></span></span> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Background and Aim:</span></span></b><b> </b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Food insecurity and poor quality of diet are among risk factors of cardiovascular diseases (CVD).</span></span> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">The main objective of this study was to assess the association of food insecurity with atherogenic glucose and lipid profile in women.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Materials and Methods:</span></span></b><b> </b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">In this cross-sectional study, 630 women between 18 and 50 years of age were selected by cluster sampling and interviewed face-to-face. To assess the household&rsquo;s food security status, we used a household food insecurity access scale (HFIAS) questionnaire, which its validity and reliability had been determined in the Iranian population. The serum levels of glucose (FBS), triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were measured and LDL/HDL, TC/HDL, and TG/HDL ratios were calculated.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Results: </span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">The mean serum concentrations of TG and TG/HDL ratio were significantly higher in the women suffering from moderate and severe food insecurity compared to those in the food-secure women (<i>p</i>=0.002). Compared with the food secure group, women with moderate and severe food security were more likely to develop hypertriglyceridemia (adjusted OR, 1.63; <i>p</i>=0.018) and a high TG/HDL ratio (adjusted OR, 1.52; <i>p</i>=0.030). However, food security status showed no significant associations with the probability of having the impaired fasting glucose, hypercholesterolemia, high LDL, low HDL, and abnormal ratios of LDL/HDL and TC/HDL.</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""> Food insecurity may be associated with increased risk of hypertriglyceridemia and high TG/HDL in women. </span></span></span></span></span><br> &nbsp; امنیت غذایی, چربی خون, گلوکز خون, بیماری‌های قلبی عروقی, زنان Food security, lipid profile, Blood glucose, Cardiovascular diseases, Women 131 143 http://sjku.muk.ac.ir/browse.php?a_code=A-10-7052-1&slc_lang=fa&sid=1 Soudabeh Hamedi-Shahraki سودابه حامدی شهرکی s.hamedy1@gmail.com 5400319475328460059740 5400319475328460059740 No Department of Epidemiology and Biostatistics, Faculty of Public Health, Zabol University of Medical Sciences, Zabol, Iran, گروه آمار و اپیدمیولوژی، دانشکده بهداشت، دانشگاه علوم پزشکی زابل، زابل، ایران Farshad Amirkhizi فرشاد امیرخیزی amirkhizi.f@gmail.com 5400319475328460059741 5400319475328460059741 Yes Department of Nutrition, Faculty of Public Health, Zabol University of Medical Sciences, Zabol, Iran گروه تغذیه، دانشکده بهداشت، دانشگاه علوم پزشکی زابل، زابل، ایران Fahimeh Khoushabi فهیمه خوشابی fyasiny@yahoo.com 5400319475328460059742 5400319475328460059742 No Department of Nutrition, Faculty of Public Health, Zabol University of Medical Sciences, Zabol, Iran گروه تغذیه، دانشکده بهداشت، دانشگاه علوم پزشکی زابل، زابل، ایران Fatemeh Mir فاطمه میر elahemir99@gmail.com 5400319475328460059743 5400319475328460059743 No Student Research Committee, Faculty of Public Health, Zabol University of Medical Sciences, Zabol, Iran مرکز تحقیقات دانشجویی، دانشکده بهداشت، دانشگاه علوم پزشکی زابل، زابل، ایران