fa بررسی رابطه Tei Index و شدت درگیری عروق کرونر در بیماران مبتلا به ایسکمی ناپایدار قلبی پزشکی- قلب و عروق Medicine - Cardiovascular پژوهشي اصیل Original Research <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">زمینه و هدف:</span></span></b> &nbsp;<span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">: بیماری های قلبی عروقی شایعترین علت مرگ و میر در اکثر مناطق دنیا از جمله ایران هستند. </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">Myocardial</span> <span dir="LTR" new="" roman="" style="font-family:" times="">performance index (MPI)</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> یا شاخص تای</span></span><span dir="LTR" style="font-size:12.0pt">(</span><span dir="LTR" new="" roman="" style="font-family:" times="">Tei</span><span dir="LTR" style="font-size:12.0pt">) </span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">&nbsp;امروزه معیاری قابل قبول برای عملکرد سیستولی و دیاستولی قلب و در واقع منعکس کننده عملکرد کلی قلب است.</span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">اطلاعات قابل قبولی در زمینه ی </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">MPI</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> در بیماران با بیماری عروق کرونر ناپایدار وجود ندارد. به همین دلیل بر آن شدیم تا در مطالعه حاضر به بررسی ارتباط بین شاخص تای (</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">Tei Index</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">) و شدت درگیری عروق کرونر بپردازیم.</span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="text-autospace:none"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">مواد و روشها</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">: رابطه</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">بین</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">شاخص</span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Tei</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">اندازه گیری</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">شده</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">به</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">دو</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">روش</span></span> <span dir="LTR" new="" roman="" style="font-family:" times="">Tissue</span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">و</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">داپلر</span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">continuous</span></span> &nbsp;<span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">و</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">شدت</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">درگیری</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">عروق</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">کرونردر</span></span><span dir="LTR" style="font-size:12.0pt"> 170</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">بیمار</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">بیمار</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">مورد</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">مطالعه</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">ارزیابی</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">شد. شاخص</span></span> <span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Tei</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">بزرگتر</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">از55/0</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">اندازه</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">گیری</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">شده</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">به</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">روش</span></span> <span dir="LTR" new="" roman="" style="font-family:" times="">Tissue</span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">و</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">0/4</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">به</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">روش داپلر</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">continuous</span> <span style="font-size:12.0pt"><span b="" style="font-family:" zar="">&nbsp;غیرنرمال</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">در</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">نظر</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">گرفته</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">شد. در نهایت ارتباط شاخص </span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Tei</span></span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> با یافته های آنژیوگرافی بیماران مورد بررسی قرار گرفت.</span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">یافته ها</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">: </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">میانگین سنی کل افراد مورد مطالعه </span></span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">10/62</span></span><span lang="FA" style="font-size:12.0pt">&plusmn;</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">58/26</span></span> <span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">سال بود. رابطه شاخص </span></span>Tie <span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">اندازه گیری شده به دو روش، با شدت درگیری عروق کرونر(</span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">1VD</span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:12.0pt">2VD</span><span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> و </span></span><span dir="LTR" style="font-size:12.0pt">3VD</span><span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">) به تفکیک جنس و به طور کلی از نظر آماری معنادار نبود(0/072</span></span> <span dir="LTR" style="font-size:12.0pt">P=</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">و </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">0/67&nbsp;</span></span><span dir="LTR" style="font-size:12.0pt">P=</span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">) </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">در روش </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">Tissue</span> <span lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">میزان شاخص با سن بیماران افزایش می یافت که معنادار بود. </span></span><span dir="LTR" style="font-size:12.0pt"></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">نتیجه گیری</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">: در بررسی رابطه بین شدت درگیری عروق کرونر (درگیری یک، دو، و سه رگ) با میانگین شاخص </span></span><span dir="LTR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Tei</span></span><span lang="FA" style="font-size:12.0pt"><span b="" style="font-family:" zar=""> اندازه گیری شده در بیماران با ایسکمی ناپایدار قلبی رابطه معنادار آماری وجود ندارد.</span></span></span></span></span></span></span></span></span> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Background and aim</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">: Cardiovascular diseases are the main cause of death worldwide. The myocardial performance index (Tei index) is an accepted method for the evaluation of the systolic and diastolic function of the heart. There is not enough data about the association between the Tei index and the severity of unstable angina disease. In this study, we evaluated the association between the Tei index and unstable angina.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Material and methods</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">: The association between the Tei index measured by two different methods (tissue and continuous Doppler) and the severity of coronary artery disease in 170 adult patients was evaluated. The Tei index higher than 0.55 in tissue Doppler and 0.4 in continuous Doppler methods were considered as abnormal. Finally, the association between the Tei index and angiography findings was evaluated.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Results</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">: The mean age of patients was 58.26&plusmn;10.62 years. The association between Tei index measured by the two methods mentioned above and the severity of coronary artery disease was not significant statistically. (p value=0.67 and 0.072 respectively)</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Conclusion</span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">: there is no association between the severity of coronary artery disease (1-3 vessel disease) and the Tei index in patients with unstable angina.</span></span></span></span></span></span></span><br> <br> &nbsp; اندکس Tei , ایسکمی ناپایدار قلبی, بیماری عروق کرونر, اکوکاردیوگرافی Tei index, unstable angina, coronary artery disease, echocardiography 59 67 http://sjku.muk.ac.ir/browse.php?a_code=A-10-6797-1&slc_lang=fa&sid=1 Akram Shariati اکرم شریعتی shariatiakram2016@gmail.com 5400319475328460070386 5400319475328460070386 No Department of Cardiology, Urmia University of Medical Sciences, Urmia, Iran استادیار قلب و عروق، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران Rogayeh Afsar Gharebagh رقیه افسر قره باغ gharebagh.r@umsu.ac.ir 5400319475328460070387 5400319475328460070387 No Associate Professor of Cardiology, school of Medicine, Urmia University of Medical Sciences, Urmia, Iran دانشیار قلب و عروق، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران Alireza Rostamzadeh علیرضا رستم زاده rostamzadeh.a@umsu.ac.ir 5400319475328460070388 5400319475328460070388 No Associate Professor of Cardiology, school of Medicine, Urmia University of Medical Sciences, Urmia, Iran دانشیار قلب و عروق، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران Nazanin Sadeghifar نازنین صادقی فر nazaninsadeghifar1@gmail.com 5400319475328460070389 5400319475328460070389 No Medical Student, Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran دانشجوی پزشکی، کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران Nazila Pashaei نازیلا پاشایی nazila.pashaei@gmail.com 5400319475328460070390 5400319475328460070390 No Medical Student, Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran دانشجوی پزشکی، کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران Reza Hajizadeh رضا حاجی زاده hajizadh.reza@gmail.com 5400319475328460070391 5400319475328460070391 Yes Assistant Professor of Cardiology, school of Medicine, Urmia University of Medical Sciences, Urmia, Iran استادیار قلب و عروق، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران