fa تاثیر 12 هفته تمرینات ورزشی منتخب پیلاتس بر سطح سرمی آدیپونکتین و مقاومت به انسولین در زنان نجات یافته از سرطان پستان و نقش آن در پیشگیری از عود بیماری عمومى General پژوهشي اصیل Original Research <p></p> <p dir="RTL" style="margin: 0in 0in 0pt text-align: justify unicode-bidi: embed direction: rtl"><font color="#000000"><b><span b="" lang="FA" new="" span="" style="line-height: 107% font-family:" times="">با توجه به تاثیر پایین بودن سطح سرمی آدیپونکتین بر بروز بیماری سرطان پستان و احتمال افزایش آن پس از یک دوره تمرینات ورزشی که ممکن است با تغییرات مقاومت به انسولین نیز همراه باشد، پژوهش حاضر با هدف شناخت تاثیر 12 هفته تمرینات ورزشی منتخب پیلاتس بر سطح سرمی آدیپونکتین و مقاومت به انسولین در زنان نجات یافته از سرطان پستان و نقش آن در پیشگیری از عود بیماری انجام شد. </span></b></font></p> <p></p> <p dir="RTL" style="margin: 0in 0in 0pt text-align: justify unicode-bidi: embed direction: rtl"><b><font color="#000000"><b><span b="" lang="FA" new="" span="" style="line-height: 107% font-family:" times="">در این مطالعه نیمه تجربی<b>،</b> 27 بیمار نجات یافته از سرطان پستان با میانگین سنی 19/6</span><span lang="FA" style="line-height: 107% font-family:">±</span><span 44="" b="" lang="FA" new="" span="" style="line-height: 107% font-family:" times="">24/29 کیلو گرم بر متر مربع بر اساس معیارهای ورود به مطالعه انتخاب شدند و سپس به طور تصادفی به دو گروه کنترل (13نفر) و تجربی (14نفر) تقسیم شدند. آزمودنی‏های گروه تجربی به مدت 12 هفته (3 جلسه در هفته) در تمرینات ورزشی منتخب پیلاتس شرکت کردند. گروه کنترل در طی این دوره در هیچ برنامه تمرین ورزشی شرکت نداشتند. داده ها با استفاده از آزمون </span><span b="" dir="LTR" new="" style="line-height: 107% font-family:" times="">t</span><span b="" color="#000000" dir="RTL" font="" lang="FA" new="" p="" span="" style="font-family:" times="">یافته ها:</span></b><span b="" dir="LTR" lang="FA" new="" span="" style="font-family:" times=""> پس از 12 هفته تمرینات ورزشی منتخب پیلاتس به طور معنی داری افزایش یافت(01/0</span><span lang="FA" new="" style="font-family:" times="">></span><span b="" dir="LTR" new="" style="font-family:" times="">(P</span><span b="" dir="LTR" lang="FA" new="" span="" style="font-family:" times=""> تغییر معنی داری نداشت (05/0</span><span lang="FA" new="" style="font-family:" times="">></span><span b="" dir="LTR" new="" style="font-family:" times="">(P</span><span .="" b="" color="#000000" dir="RTL" font="" lang="FA" new="" p="" span="" style="line-height: 107% font-family:" times="">نتیجه گیری:</span></font></b><font color="#000000"><span b="" lang="FA" new="" span="" style="line-height: 107% font-family:" times="">یابد، به نظر می رسد شرکت این افراد در تمرینات پیلاتس می تواند مانع عود سرطان پستان شود. </span></font></p> <p></p> <p dir="RTL" style="margin: 0in 0in 0pt text-align: justify unicode-bidi: embed direction: rtl"><font color="#000000"><b><span b="" lang="FA" new="" span="" style="line-height: 107% font-family:" times="">سرطان پستان، آدیپونکتین، مقاومت به انسولین، پیلاتس</span></b></font></p> <p><b><font color="#000000"><span lang="FA" style="line-height: 107% font-family:" dir="RTL" roman""="" new="" "times="" roman"="" fa="" 12pt="" zar"="" b="" en-us="" zwadobef="">وصول مقاله :25/5/94<span style="mso-spacerun: yes">  </span>اصلاحیه نهایی:16/6/94 پذیرش:21/6/94</font></b></p> <p></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"><font color="#000000"><span b="" new="" style="font-family:" times=""><b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar"">Background and Aim:</span></b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar""> A low level of adiponectin have a great effect on the breast cancer incidence and increase in adiponectin after a period of exercise training may be associated with changes in insulin resistance. Therefore, the present study aimed to investigate the effect of 12 weeks of selected Pilates exercise training on serum adiponectin level and insulin resistance in female survivors of breast cancer and its role in prevention of the recurrence.</span></span></font></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"><font color="#000000"><span b="" new="" style="font-family:" times=""><b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar"">Material and Methods:</span></b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar""> 27 breast cancer survivors (mean age 44.11±6.19 years old, BMI 29.24±4.92 kg/m²) were selected based on our inclusion criteria and randomly divided into experimental (n=14) and control (n=13) groups. The experimental group participated in a 12 weeks of selected Pilates exercise training (three session per week). During this period, the control group did not participate in any exercise training program. Data were analyzed using paired and independent t-test.</span></span></font></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal -ms-text-autospace: mso-layout-grid-align: none"><font color="#000000"><span b="" new="" style="font-family:" times=""><b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar"">Results:</span></b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar""> Serum adiponectin level and VO₂max significantly increased, but insulin level, insulin resistance and body fat percentage significantly decreased and the FBS level had no </span><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Nazanin"">significant change</span><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar""> after selected Pilates exercise training (P<0.05).</span></span></font></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"><font color="#000000"><span b="" new="" style="font-family:" times=""><b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar"">Conclusion:</span></b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar""> Considering the increase in adiponectin level and decrease in insulin resistance after selected Pilates exercise training, it seems participation of the breast cancer survivors in Pilates exercise training can prevent breast cancer recurrence.</span></span></font></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"><font color="#000000"><span b="" new="" style="font-family:" times=""><b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar"">Keywords:</span></b><span style="font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: FA mso-bidi-font-family: "B Zar""> Breast cancer, Adiponectin, Insulin resistance, Pilates</span></span></font></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 8pt"><font color="#000000"><span b="" new="" style="font-family:" times=""><font size="3"> </font></span></font></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"><font color="#000000"><span b="" new="" style="font-family:" times=""><b><span lang="EN-GB" style="line-height: 107% font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: AR-SA mso-ansi-language: EN-GB mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi">Received: </span></b><span lang="EN-GB" style="line-height: 107% font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: AR-SA mso-ansi-language: EN-GB mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi">Aug </span><span style="line-height: 107% font-family: "Times New Roman","serif" font-size: 11pt mso-bidi-language: AR-SA mso-ansi-language: EN-US mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi">16</span><span lang="EN-GB" style="line-height: 107% font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: AR-SA mso-ansi-language: EN-GB mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi">, 2015<b><span style="mso-spacerun: yes">      </span>Accepted: </b></span><span lang="EN-GB" style="line-height: 107% font-family: "Times New Roman","serif" font-size: 11pt mso-bidi-language: AR-SA mso-ansi-language: EN-GB mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi">Sep</span><span lang="EN-GB" style="line-height: 107% font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: AR-SA mso-ansi-language: EN-GB mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi"> </span><span lang="EN-GB" style="line-height: 107% font-family: "Times New Roman","serif" font-size: 11pt mso-bidi-language: AR-SA mso-ansi-language: EN-GB mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi">12</span><span lang="EN-GB" style="line-height: 107% font-family: "Times New Roman","serif" font-size: 12pt mso-bidi-language: AR-SA mso-ansi-language: EN-GB mso-fareast-font-family: ZWAdobeF mso-fareast-language: EN-US mso-ascii-theme-font: major-bidi mso-hansi-theme-font: major-bidi mso-bidi-theme-font: major-bidi">, 2015</span></span></font></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> <p style="margin: 0in 0in 0pt text-align: justify line-height: normal"></p> سرطان پستان, آدیپونکتین, مقاومت به انسولین, پیلاتس Breast cancer, Adiponectin, Insulin resistance, Pilates 61 73 http://sjku.muk.ac.ir/browse.php?a_code=A-10-25-32&slc_lang=fa&sid=1 Akbar Azamian jazi اکبر اعظمیان جزی azamianakbar@yahoo.com 540031947532846008624 540031947532846008624 Yes Behnam Ghasemi Mobarekeh بهنام قاسمی مبارکه 540031947532846008625 540031947532846008625 No Zaynab Vismeh زینب ویسمه 540031947532846008626 540031947532846008626 No Noshin Parsa Gohar نوشین پارساگهر 540031947532846008627 540031947532846008627 No