@ARTICLE{Izadi, author = {Izadi, Mojtaba and Aghdami, Anoosh and Khorshidi, Davoud and Ahmadi, Saba and Doali, Hosain and Kyani, Fatemeh and }, title = {The effect of chronic L-Carnitne supplementation on plasma glucose and lactate during exercise}, volume = {13}, number = {4}, abstract ={Background and Aim: In skeletal muscle, carnitine plays an essential role in the translocation of long-chain fatty-acids into the mitochondrial matrix for subsequent beta-oxidation. Despite an abundance of literature describing the basic mechanisms of action of L-carnitine metabolism, there remains some uncertainty regarding the effects of oral L-carnitine supplementation on metabolism and exercise performance in normal subjects. This study examined the effects of chronic L-carnitine supplementation on glucose and lactate concentration, heart rate and aerobic capacity during submaximal cycling. Material and Methods: Thirty healthy and male students cycled for 20 min at 70% VO2 max before and after 3 weeks (3g daily) L-carnitine (experimental) and placebo (control) supplementation. Blood samples were taken immediately after each exercise for the purpose of calculation plasma glucose and Lactate concentration, lactate dehydrogenase activity (LDH). A two-way repeated measure ANOVA was used to determine significant differences between the two groups (p }, URL = {http://sjku.muk.ac.ir/article-1-96-en.html}, eprint = {http://sjku.muk.ac.ir/article-1-96-en.pdf}, journal = {Scientific Journal of Kurdistan University of Medical Sciences}, doi = {}, year = {2009} }