TY - JOUR T1 - Effects of Permethrin on sexual behaviour and plasma concentrations of pituitary-gonadal hormones in adult male NMRI mice TT - بررسی اثرات حشره کش پرمترین ((permethrin بر روی هورمونها و رفتارهای جنسی موشهای سوری نر بالغ نژاد NMRI JF - HBI_Journals JO - HBI_Journals VL - 13 IS - 2 UR - http://sjku.muk.ac.ir/article-1-62-en.html Y1 - 2008 SP - 42 EP - 49 KW - Insecticide KW - Permethrin KW - Sexual hormones KW - sexual behavior N2 - ABSTRACT Background and Aim: Pyrethroids are commonly used as insecticides for both household and agricultural purposes, and recently have been shown to have detrimental effects on endocrine system. Permethrin is a type I pyrethroid which is used widely in Iran. In the present study the effects of permethrin on sexual behaviour and plasma level of PG (pituitary-gonadal) hormones of adult male mice were investigated. Material and Methods: Mice received daily Intra peritoneal injection of permethrin (10, 15, 20 mg/kg) for 5 weeks. Using receptive females, permethrin-treated male mice exhibited reduced sexual behavior (i.e. decrease in the number of sniffing, following, mounting and mating). Results: The concentrations of plasma testosterone, LH and FSH were measured by means of ELISA method. Serum testosterone levels were reduced significantly (p M3 ER -