@ARTICLE{Abbasivash, author = {Abbasivash, Rahman and Aghdashi, Mir Moosa and Hasani, Ebrahim and Heshmati, Farhad and Shirvani, Mohammad and Rahimi, Ezatollah and }, title = {The effect of addition of intravenous nitroglycerin to lidocaine for improvement of quality of intravenous regional anesthesia}, volume = {13}, number = {2}, abstract ={ABSTRACT Background and Aim: Disadvantages of intravenous regional anesthesia (IVRA) include slow onset, poor muscle relaxation, tourniquet pain, and rapid onset of pain after tourniquet deflation. In this randomized, double-blind study, we evaluated the effect of addition of nitroglycerine (NTG) to lidocaine for improvement of IVRA. Material and Methods: Forty six patients (20-50 yrs) were randomly assigned into 2 equal groups. Under identical conditions, the control group received 3 mg/kg of lidocaine 0.5% diluted with saline, and the study group received an additional 200 µg NTG. Vital signs and tourniquet pain were measured on the basis of VAS score and recorded before applying tourniquet and 5, 10, 15, 20, and 30 min after administration of anesthetic solution. The onset of sensory and motor block was measured and recorded for all patients. Severity of pain was measured at 5 min, 2, 4, 6, 12, 24, hours after deflation of tourniquet and the total dosage of pethidin injected in the first 24 hours after operation was calculated. Results: Sensory and motor block began more rapidly in study group than control group (2.61 vs. 5.09 and 4.22 vs. 7.04 min., respectively) (p }, URL = {http://sjku.muk.ac.ir/article-1-57-en.html}, eprint = {http://sjku.muk.ac.ir/article-1-57-en.pdf}, journal = {Scientific Journal of Kurdistan University of Medical Sciences}, doi = {}, year = {2008} }