TY - JOUR T1 - The effects of cigarette or waterpipe smoke and immobilization on serum levels of TSH, T3 or T4 in male rats TT - بررسی اثرات توام دود سیگار یا دود قلیان وبی حرکتی مزمن برسطوح سرمیTSH ، T3 و T4 در موشهای صحرایی نر JF - HBI_Journals JO - HBI_Journals VL - 18 IS - 3 UR - http://sjku.muk.ac.ir/article-1-1125-en.html Y1 - 2013 SP - 47 EP - 54 KW - Cigarette KW - Water pipe KW - Immobilization KW - TSH KW - T3 KW - T4 KW - Rat. N2 - ABSTRACT Background and Aim: The results of different studies have shown smoking can influence functions of thyroid gland. The aim of this study was to determine the effects of cigarette or water pipe smoking and immobilization on serum levels of TSH, T3 and T4 in male rats. Material and Methods: In this laboratory experimental study, male Wistar rats were randomly divided into the following groups: control,rats exposed to cigarette smoke ,rats exposed to waterpipe smoke, chronically immobilized rats, and chronically immobilized rats exposed to cigarette or waterpipe smoke. Each group consisted of 5 rats. After 6 weeks blood samples were collected by cardiac puncture method. After obtaining serum, levels of TSH, T3 or T4 were measured by radioimmunoassay method. Data were statistically analyzed and compared among the groups by means of one way ANOVA. Results: Serum TSH levels were not significantly changed in experimental groups comaperd to control animals. Serum T3 and T4 levels were significantly increased in rats exposed to waterpipe smoke as compared to control animals (P M3 ER -