TY - JOUR T1 - Study of prevalence of neonatal Septicaemia and detection of antibiotic resistance in Besat Hospital in Sanandaj in 1383 TT - بررسی شیوع سپتی‌سمی نوزادان و تعیین مقاومت دارویی نسبت به آنتی‌بیوتیکها در بیمارستان بعثت سنندج درسال 1383 JF - HBI_Journals JO - HBI_Journals VL - 10 IS - 4 UR - http://sjku.muk.ac.ir/article-1-195-en.html Y1 - 2006 SP - 26 EP - 32 KW - Neonatal septicemia KW - Antibiotic resistant N2 - ABSTRACTBackground and Aim: which occurrs as a result of bacterial infection. The major criterion for its diagnosis isbased on body fluid cultures specially blood culture. The aim of this study is todetermine the prevalence of septicemia and also detection of isolated bacterialsensitivity to selected antibiotics in neonatal ward of Besat Hospital.Septicemia is one of the most important neonatal diseasesMaterials and Methods: hospitalized neonates. A questionnaire including clinical manifestations of septicemiasuch as fever, hyporeflexia, hypothermia, cyanosis, abdominal distention, loss ofappetite and jaundice was filled out for every neonate clinically suspected of havingsepticemia. At last the collected data were analyzed by means of SPSS software anddescriptive statistics.This study is descriptive. Blood cultures were ordered for allResults: suspected of having septicemia but %30 of them had positive blood cultures. Themost common species isolated was coagulase negative staphylococci. As to sign andsymptoms hyporeflexia, juandice, and anorexia were detected most frequently.Sensitivity of gram negative bacteria to ciprofloxacin was %100 & to cefotaxime%66.7. Sensitivity of gram positive bacteria to cephalotin was %43, while gramnegative bacteria had highest resistance rate to ampicilin & cephalotine in %100 andgram positive bacteria to oxacilin in %68.6 & cotrimoxasol in %62.9 of the cases. Inthis study prevalence of septicemia in those having positive blood cultures was 30%with a mortality rate of 4.9%.This study included 700 specimen of blood cultures, %17.6 of the cases wereConclusion: diagnosis of septicemia and blood cultures should be considered necessary insuspected cases. Considering high resistance rate of isolated bacteria to ampicilin &cephalotin, culture and antibiogram can be of great value to select suitable antibioticThis research shows that clinical manifestation is not enough for the.Ciprofloxacin can be regarded as the drug of choice for gram negative bacteria. Toreduce prevalence and mortality rates of septicemia, proper planning to confrontmicroorganisms & nosocomial infections is necessary. Also appropriate and timelyprescription of antibiotics by pediatricians can prevent bacterial resistance toantibiotics. M3 ER -