:: Scientific Journal of Kurdistan University of Medical Sciences- NO 4, 2024 -Articles In press ::
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Hematological factors and MRI in covid-19 infected may predict the prevalence of multiple sclerosis in the post-Covid era
Bakhtiar Ebrahimirad1 , Mahnaz Taherianfard 2, Arash Mosarezaii3
1- Shiraz University
2- Shiraz University , taherian@shirazu.ac.ir
3- Urmia Medical University
Abstract:   (530 Views)
Background and Aim: This study aimed to compare blood factors and MRI in MS+ participants (with a history of MS) and MS- (without a history of MS) to determine the prevalence of MS in MS- and increase the severity of the disease in MS+.
Materials and Methods: In this cross-sectional-observational study, according to the newspaper announcement, 80 human samples were chosen from 20-50-year-olds infected with Covid-19 based on the PCR test at the time of infection from Esfand 1st, 1398 to Aban 30th, 1400. The research method was explained to all participants, who filled out and signed an informed consent form. CBC, ESR, ANA, and CRP were measured in the participants' blood samples. Then, an MRI scan was done on all participants to diagnose MS.
Results: In age groups 31-40 and 41-50, ANA was significantly higher in MS+ than MS- participants. ANA was meaningfully higher in inpatient and outpatient MS+ than in inpatient and outpatient MS-. In MS+ men, CRP was higher than in MS- men. The MRI scan showed that MS plaques were observed in 13 patients with no history of MS before contracting Covid-19.
Conclusion: The results showed that CRP and ANA were higher than healthy in all participants 2.5 years after the infection of Covid-19, but this increase was more in hospitalized and MS+ participants. Also, the MRI showed MS plaques after contracting Covid-19.
 
Keywords: Covid-19, Multiple sclerosis, C-reactive protein, antinuclear antibodies, Erythrocyte sedimentation rate
     
Type of Study: Original Research | Subject: Physiology and neurosciences
Received: 2023/08/2 | Accepted: 2023/11/4

Ethics code: IR.US.REC.1401.033


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