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The frequency of Toxoplasma and Cytomegalovirus infections in HIV-positive patients in HIV/AIDS counseling and care center in Kurdistan in 1385
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Shahla Afrasiabian   1, Katayoon Hajibagheri , Vahid Yousefinejad , Shohreh Rezaiee , Farokh Shahmoradi |
| 1- , shahlaafra@yahoo.com |
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Abstract: (15367 Views) |
| ABCTRACT
Background and Aim: Cytomegalovirus (CMV) and toxoplasmosis are the most common and serious opportunistic infections in AIDS patients. Despite recent advances in the treatment of these infections, they still remain as challenging problems for physicians. The aim of this study was to determine the frequency of cytomegalovirus and toxoplasma infections in HIV-positive patients in HIV/AIDS counseling and care center in Kurdistan in 1385.
Material and Methods: This was a cross-sectional descriptive, analytic study. The sample size included all accessible patients referring to Sanandaj behavioral and STD diseases consultation center (64 participants). ELISA test was performed for all individuals, IgM and IgG anti CMV and Toxoplasma titers were determined. Data were introduced into SPSS 13 Soft ware and analyzed by one way ANOVA test.
Results: This study included 64 patients, 98/4% of them were male. The mean age of the patients was 32.1±6.73 years. Anti cytomegalovirus IgM was negative and anti cytomegalovirus IgG was positive in all of the patients (100%). Anti Toxoplasma IgM and anti Toxoplasma IgG were positive in 10.9% and 46.9% of the patients respectively. There was no significant relationship between the level of IgG and mean time duration of being HIV positive, age and CD4 cell count. But a significant relationship was noticed between the level of CMV and toxoplasma IgM and CD4 cell count (p<0.05). There was a significant relation between positive toxoplasmosis IgM and history of keeping a pet in house (p=0.019).
Conclusion: In this study 100% of HIV positive participants were negative for anti cytomegalovirus IgM which can be explained by presence of CD4 cell count above 100 in all of the patients. But 53% of HIV positive participants had negative anti toxoplasma antibody who will be at risk of acute toxoplasmosis in their clinical course. Educational plans and regular follow up of theses patients are recommended for proper prophylaxis and treatment.
Key words: HIV/AIDS, Toxoplasma Gondeii, Cytomegalovirus, Serology.
Conflict of Interest: Nill
Received: May 15, 2008 Accepted: June 18, 2008 |
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| Keywords: HIV/AIDS, Toxoplasma Gondeii, Cytomegalovirus, Serology. |
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Full-Text [PDF 126 kb]
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Type of Study: Original Research |
Subject:
General
Received: 2009/04/11 | Published: 2008/09/15
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